Results 1 to 10 of about 44,302 (175)

A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents. [PDF]

open access: yesPLoS ONE, 2015
Studies have demonstrated that oncolytic adenoviruses based on a 24 base pair deletion in the viral E1A gene (D24) may be promising therapeutics for treating a number of cancer types.
G Clement Dobbins   +3 more
doaj   +7 more sources

When Classic Signs Deceive: A Widespread Papulosquamous Eruption in Skin of Colour [PDF]

open access: yesDermatopathology
A 29-year-old gentleman of African descent presented to the emergency department with a three month history of a rash affecting the trunk, upper limbs, and thighs.
Ji Fung Yong   +4 more
doaj   +2 more sources

Ad6-Based GM-CSF Expressing Vector Displays Oncolytic and Immunostimulatory Effects in an Immunocompetent Syrian Hamster Model of Cholangiocarcinoma [PDF]

open access: yesViruses
Cholangiocarcinoma (CCA), the second most common liver cancer, remains highly resistant to chemotherapy and radiotherapy, leaving patients with unresectable tumors in urgent need of innovative therapeutic approaches.
Daria S. Zabelina   +10 more
doaj   +2 more sources

Personalized management of hypertensive patients: focus on prognostic biomarkers

open access: yesРоссийский кардиологический журнал, 2022
Aim. To analyze level of circulating biomarkers of plasma vascular endothelial growth factor (VEGF) and tumor necrosis factor-α (TNF-α) during 3-month therapy with a fixed-dose combination of ramipril/indapamide (Konsilar-D24, AO Vertex, Russia), as well
S. V. Lyamina   +2 more
doaj   +1 more source

Small-Bowel Capsule Endoscopy—Optimizing Capsule Endoscopy in Clinical Practice

open access: yesDiagnostics, 2021
The small bowel is the longest organ within the gastrointestinal tract. The emergence of small bowel capsule endoscopy (SBCE) over the last 20 years has revolutionized the investigation and diagnosis of small bowel pathology.
Fintan O’Hara, Deirdre McNamara
doaj   +1 more source

The challenge of primary gastric melanoma: a systematic review

open access: yesMelanoma Management, 2020
Aim: Primary gastric melanoma is a rare clinical presentation. The purpose of this review was to compare the 1-year survival in patients who underwent surgery with patients who did not receive treatment.
Gregory S Mellotte   +5 more
doaj   +1 more source

Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity

open access: yesJournal for ImmunoTherapy of Cancer, 2020
Background Ovarian cancers often contain significant numbers of tumor-infiltrating lymphocytes (TILs) that can be readily harnessed for adoptive T-cell therapy (ACT).
Akseli Hemminki   +11 more
doaj   +1 more source

Analytic solutions for Dp branes in SFT [PDF]

open access: yes, 2011
This is the follow-up of a previous paper [ArXiv:1105.5926], where we calculated the energy of an analytic lump solution in SFT, representing a D24-brane. Here we describe an analytic solution for a Dp-brane, for any p, and compute its energy.Comment: 14
Bonora, L., Giaccari, S., Tolla, D. D.
core   +2 more sources

Human resources quality improvement from the perspective of Kaizen practices

open access: yesManagement, 2022
Kaizen has long been known as an improvement philosophy that starts with small frequent changes to make larger changes in production. These changes come from the ideas and creative thinking of employees to ensure that the production conditions and ...
Minh Nguyen Dat, Quyen Nguyen Thi Hanh
doaj   +1 more source

Renormalization Group Analysis of Tachyon Condensation [PDF]

open access: yes, 2001
Renormalization group analysis of boundary conformal field theory on bosonic D25-brane is used to study tachyon condensation. Placing the lump on a finite circle and triggering only the first three tachyon modes, the theory flows to nearby IR fixed point
Dasgupta, Satabhisa, Dasgupta, Tathagata
core   +2 more sources

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