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Effects of a New Analgesic Agent, D57, on Sodium Currents in Afferent Neurons of the Rat Ganglia
Neurophysiology, 1999We studied the effects of a new analgesic agent, D57 (a pyrrolimidazol derivative), on sodium currents in isolated afferent neurons of the trigeminal and spinal ganglia of rats. It is demonstrated that D57 exerts both tonic and phasic effects on sodium currents.
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