Pathogenicity and virulence of Shigella sonnei : A highly drug-resistant pathogen of increasing prevalence [PDF]
Shigella spp. are the causative agent of shigellosis (or bacillary dysentery), a diarrhoeal disease characterized for the bacterial invasion of gut epithelial cells.
Abigail Clements +1 more
exaly +4 more sources
Genome-wide analysis exploring mechanisms used by Shigella sonnei to survive long-term nutrient starvation [PDF]
Shigella is a major cause of severe diarrhea, with Shigella flexneri and Shigella sonnei accounting for over 90% of infections. Progressive economic growth worldwide correlates with the replacement of S. flexneri by S.
Xosé M. Matanza +6 more
doaj +2 more sources
Divergent Evolution and Local Establishment of Multidrug-Resistant <i>Shigella sonnei</i> in China. [PDF]
• Evolutionary history and local establishment of Chinese Shigella sonnei are unclear. • Chinese S. sonnei developed into four clades and ONPG‐negative variants. • The antimicrobial resistance phenotype of Clade I was due to an IncB/O/K/Z plasmid. • Antimicrobial resistance of Clade II was due to IncFII and IncB/O/K/Z plasmids.
Liu K +26 more
europepmc +2 more sources
Genetic relatedness among isolates of
Background Shigella spp. are major cause of diarrhoeal disease in both developing and developed countries. Shigella sonnei is the serogroup of Shigella most frequently responsible for sporadic and epidemic enteritis in developed countries.
Sadeghifard Nourkhoda +5 more
doaj +4 more sources
Macrolide-Resistant Shigella sonnei
Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides ...
Leyla Boumghar-Bourtchai +7 more
doaj +5 more sources
Extended spectrum β-lactamase and integron genes among Shigella flexneri and Shigella sonnei isolated from children with diarrhea in shiraz, Southwest Iran [PDF]
Shigellosis, a bacterial infection marked by dysentery, is typically a self-limiting disease and can be effectively managed with oral rehydration. However, antibiotics may help reduce the severity and duration of Shigellosis despite rising antimicrobial ...
Keyvan Farhadi +5 more
doaj +2 more sources
Shigella sonnei: virulence and antibiotic resistance [PDF]
Shigella sonnei is the emerging pathogen globally, as it is the second common infectious species of shigellosis (bloody diarrhoea) in low- and middle-income countries (LMICs) and the leading one in developed world. The multifactorial processes and novel mechanisms have been identified in S. sonnei, that are collectively playing apart a substantial role
Ahtesham Ahmad Shad
exaly +3 more sources
THE SPECIFIC ANTIGENS OF VARIANTS OF SHIGELLA SONNEI [PDF]
It has been shown that phase variation of Sh. sonnei is accompanied by changes in morphology and antigenic structure. Two mutants of the Phase I organism (IIS and IIR), which were studied, elaborate somatic antigens which are immunologically identical.
E E, BAKER, W F, GOEBEL, E, PERLMAN
exaly +3 more sources
Cross-comparison study of three ELISA methodologies to measure Shigella Sonnei O-antigen serum IgG [PDF]
Measurement of serum immunoglobulin G (IgG) to Shigella lipopolysaccharide (LPS) has been proposed as a correlate of protection against shigellosis, the confirmation of which in the target population of infants in low- and middle-income countries will ...
Paul Stickings +13 more
doaj +2 more sources
Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella [PDF]
Shigella is a leading cause of diarrheal morbidity and mortality in young children from low- and middle-income countries. Here, we aimed to verify the ability of the generalized modules for membrane antigens (GMMA)-based Shigella sonnei candidate vaccine
Arlo Z. Randall +21 more
doaj +2 more sources

