Results 11 to 20 of about 30,065 (206)

Pathogenicity and virulence of Shigella sonnei: A highly drug-resistant pathogen of increasing prevalence [PDF]

Virulence, 2023
Shigella spp. are the causative agent of shigellosis (or bacillary dysentery), a diarrhoeal disease characterized for the bacterial invasion of gut epithelial cells.
Xosé Manuel Matanza Fente, Abigail Clements   +1 more
exaly   +5 more sources

Macrolide-Resistant Shigella sonnei

Emerging Infectious Diseases, 2008
Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides ...
Leyla Boumghar-Bourtchai, Patricia Mariani-Kurkdjian, Edouard Bingen, Ingrid Filliol, Anne Dhalluin, Shadia Ait Ifrane, François-Xavier Weill, Roland Leclercq   +7 more
doaj   +6 more sources

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation [PDF]

mBio, 2019
Two Shigella species, Shigella flexneri and Shigella sonnei, cause approximately 90% of bacterial dysentery worldwide. While S. flexneri is the dominant species in low-income countries, S.
Jayne L. Watson, Julia Sanchez-Garrido, Philippa J. Goddard, Vincenzo Torraca, Serge Mostowy, Avinash R. Shenoy, Abigail Clements   +6 more
doaj   +2 more sources

Genome-wide analysis exploring mechanisms used by Shigella sonnei to survive long-term nutrient starvation [PDF]

mSystems
Shigella is a major cause of severe diarrhea, with Shigella flexneri and Shigella sonnei accounting for over 90% of infections. Progressive economic growth worldwide correlates with the replacement of S. flexneri by S.
Xosé M. Matanza, P. Brian Leung, Vincenzo Torraca, Jayne Watson, Matthew J. Dorman, Nicholas R. Thomson, Abigail Clements   +6 more
doaj   +2 more sources

Protective immunity against Shigella sonnei in vaccinated and challenged adult Thai volunteers [PDF]

mSphere
A safe, effective, and affordable vaccine that can prevent Shigella-induced diarrhea could have a significant impact on reducing morbidity and mortality in populations at risk.
Esther Ndungo, Dilara Islam, Siriphan Gonwong, Nattaya Ruamsap, Patricia L. Milletich, Alain Agnememel, Samandra T. Demons, Marcela F. Pasetti   +7 more
doaj   +2 more sources

Development and evaluation of a dual-target glycoconjugate against Shigella sonnei [PDF]

Frontiers in Immunology
IntroductionShigellosis morbidity and mortality, combined with the increase in multidrug-resistant infections, make Shigella vaccine development a global imperative.
Catherine L. Hall, Tom L. Flood, Simon Clare, Katherine Harcourt, Emily J. Kay, Stephen Baker, Brendan W. Wren   +6 more
doaj   +2 more sources

Shigella sonnei [PDF]

Trends in Microbiology, 2020
Shigella sonnei is a rod-shaped, Gram-negative facultative intracellular pathogen. It was named ‘Sonne’s bacillus’ after Carl Olaf Sonne who described it as a causative agent of bacillary dysentery. S.
Torraca, Vincenzo, Holt, Kathryn, Mostowy, Serge   +2 more
core   +8 more sources

Shigella sonnei: virulence and antibiotic resistance [PDF]

Archives of Microbiology, 2020
Shigella sonnei is the emerging pathogen globally, as it is the second common infectious species of shigellosis (bloody diarrhoea) in low- and middle-income countries (LMICs) and the leading one in developed world. The multifactorial processes and novel mechanisms have been identified in S. sonnei, that are collectively playing apart a substantial role
Ahtesham Ahmad Shad, Wajahat Ahmed Shad
exaly   +3 more sources

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. [PDF]

PLoS Pathogens, 2019
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei is replacing S. flexneri, especially in developing countries.
Vincenzo Torraca, Myrsini Kaforou, Jayne Watson, Gina M Duggan, Hazel Guerrero-Gutierrez, Sina Krokowski, Michael Hollinshead, Thomas B Clarke, Rafal J Mostowy, Gillian S Tomlinson, Vanessa Sancho-Shimizu, Abigail Clements, Serge Mostowy   +12 more
doaj   +13 more sources

Shigella flexneri and Shigella sonnei among children under five in Kenya’s urban informal settlement [PDF]

Gut Pathogens
Background Shigella species are a significant global public health threat with the highest burden of Shigella-associated diarrhoea in children under five years of age, particularly in low- and middle-income countries. Given the high burden of shigellosis
Christine Kioko, John M. Maingi, Cecilia Mbae, Phelgona Otieno, Collins Kebenei, Winfred Mbithi, Amos Njuguna, Schola Kamwethya, Diana Imoli, Darius Ideke, Jessicah Jepchirchir, Kelvin Kering, Samuel Kariuki   +12 more
doaj   +2 more sources