Results 21 to 30 of about 8,535 (171)

Acid tolerance of Shigella sonnei and Shigella flexneri [PDF]

open access: yesJournal of Applied Microbiology, 2002
Determination of the behaviour of Shigella sonnei and Sh. flexneri under acid conditions.The growth and survival of Shigella spp. (9 isolates) in acidified Brain Heart Infusion (BHI) (pH 5.0-3.25 with pH intervals of 0.25) was determined after 6, 24 and 30 h incubation at 37 degrees C.
C F, Bagamboula   +2 more
openaire   +2 more sources

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation

open access: yesmBio, 2019
Two Shigella species, Shigella flexneri and Shigella sonnei, cause approximately 90% of bacterial dysentery worldwide. While S. flexneri is the dominant species in low-income countries, S.
Jayne L. Watson   +6 more
doaj   +1 more source

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence.

open access: yesPLoS Pathogens, 2019
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei is replacing S. flexneri, especially in developing countries.
Vincenzo Torraca   +12 more
doaj   +1 more source

Genotypic characterization and antimicrobial susceptibility profile of Shigella Species isolated from different sources at Kaliobia governorate [PDF]

open access: yesBenha Veterinary Medical Journal, 2023
The current investigation focused on 13 Shigella isolates. These isolates were derived from 260 randomly sampled specimens including beef, chicken meat, cow's milk, and diarrheic child stool (with 65 samples each). The samples were collected from diverse
mennatallah habeeb   +3 more
doaj   +1 more source

Shigella-specific antibodies in the first year of life among Zambian infants: A longitudinal cohort study.

open access: yesPLoS ONE, 2021
IntroductionShigellosis, is a leading cause of moderate-to-severe diarrhoea and related mortality in young children in low and middle income countries (LMICs).
Caroline C Chisenga   +11 more
doaj   +1 more source

Impact of insertion sequences on convergent evolution of Shigella species.

open access: yesPLoS Genetics, 2020
Shigella species are specialised lineages of Escherichia coli that have converged to become human-adapted and cause dysentery by invading human gut epithelial cells.
Jane Hawkey   +4 more
doaj   +1 more source

Evaluation of a Live Attenuated S. sonnei Vaccine Strain in the Human Enteroid Model

open access: yesPathogens, 2021
Shigella is a leading cause of bacillary dysentery worldwide, responsible for high death rates especially among children under five in low–middle income countries.
Giulia Pilla   +6 more
doaj   +1 more source

Establishment of a Controlled Human Infection Model with a Lyophilized Strain of Shigella sonnei 53G

open access: yesmSphere, 2020
Controlled human infection models (CHIMs) are useful for vaccine development. To improve on existing models, we developed a CHIM using a lyophilized preparation of Shigella sonnei strain 53G produced using current good manufacturing practice (cGMP ...
Robert W. Frenck   +14 more
doaj   +1 more source

Chemical Studies on Shigella sonnei Lipid A [PDF]

open access: yesEuropean Journal of Biochemistry, 1974
Shigella sonnei lipid A isolated from lipopolysaccharides of S and R-forms of the bacteria, is composed of β-glucosaminyl-1,6-glucosamine units interlinked probably by pyrophosphate bridges (molar ratio GlcN/P 0.8:1). Glucosamine disaccharide units are O-substituted by fatty acids residues: lauryl-, 3-d-myristoxymyristoyl-, 3-d-hydroxymyristoyl- and ...
C, Lugowski, E, Romanowska
openaire   +2 more sources

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

open access: yesAngewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg   +21 more
wiley   +2 more sources

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