Results 51 to 60 of about 2,158 (184)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

Estimation of Potential and Legal Revenue Capacities of Tehran Municipality Resulting from the Provisions of the VAT Law [PDF]

اقتصاد شهری
Municipalities are responsible for providing goods and services at the city level and have a special role in increasing the welfare of citizens. To increase the share of sustainable VAT revenues of municipalities, knowledge of the potential and legal ...
Hojjat Izadkhasti, Zarir Negintaji
doaj   +1 more source

QX008N, an Anti‐TSLP Monoclonal Antibody: Pharmacokinetics, Tolerability, and Immunogenicity in Healthy Chinese Subjects

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT QX008N, a humanized IgG1 monoclonal antibody against thymic stromal lymphopoietin (TSLP) with Fc engineering to extend half‐life, was developed with the aim of exploring whether its extended half‐life and cost‐effective production could potentially address unmet needs in severe asthma therapy, such as the need for less frequent dosing and ...
Zhen‐Wei Shen, Qi Jiang, Kai‐Qi Wu, Ting‐Han Jin, Jie Zhao, Tong Guo, Min Fang, Gui‐Ling Chen   +7 more
wiley   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Genotype Differences and Hydroxyurea Utilization Among Adults With Moderate to Severe Sickle Cell Disease

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 1, January 2026.
ABSTRACT Backgrounds Hydroxyurea (HU) remains underutilized in adults with sickle cell disease (SCD) despite proven benefits. Current HU guidelines primarily target sickle cell anemia (SCA), overlooking other genotypes. Objectives This study examined HU utilization patterns across genotypes among adults considered to have moderate to severe SCD ...
Siang‐Hao Cheng, Enrico M. Novelli, Hyeun Ah Kang, Terri V. Newman, Kangho Suh   +4 more
wiley   +1 more source

PERFORMANCE OF COFFEE LEAF EXPLANTS IN SOMATIC EMBRYOGENESIS [PDF]

, 2020
Explants of four coffee genotypes: T169,C111, C314 and D57 were cultured and maintained at 27±2oC for 14 to 42 days. Calli observed were then transferred to the embryo development (ED) medium and incubated for 90 days, Matured calli were then cultured in
Balogun, S.T.
core   +1 more source

How Does the European Union's Pluralistic Institutional System Influence Policy Change? The Case of the European Union Regulation on Deforestation‐Free Products

Sustainable Development, Volume 34, Issue S1, Page 1362-1378, January 2026.
ABSTRACT How did policy actors use the European Union's (EU's) political system to achieve policy changes in regulating the sustainability and legality of transnational forest and agricultural commodity supply chains? We qualitatively analysed the development of the new EU Regulation on Deforestation‐free products (EUDR) from actor‐centred and ...
Laila Berning, Rachael D. Garrett, Metodi Sotirov   +2 more
wiley   +1 more source

Design, Modelling and Control of a MW‐level Hydrogen Converter for an Off‐Grid DC Hydrogen Production System

IET Power Electronics, Volume 19, Issue 1, January/December 2026.
This paper proposes a high‐power hydrogen converter specifically designed for megawatt‐level (MW‐scale) off‐grid hydrogen production systems powered by renewable energy sources. A two‐stage ISOP architecture is adopted to fulfill the demanding requirements of high voltage step‐up, high efficiency, low output ripple, and reliable power regulation.
Rui Zhou, Fei Xiao, Jilong Liu, Yufan Li, Shanxu Duan   +4 more
wiley   +1 more source

Una Matriz de Contabilidad Social de México y un análisis estructural de la economía mexicana

Estudios Sociales, 2010
El objetivo central de este trabajo es el de presentar una Matriz de Contabilidad Social (MCS) de la economía mexicana para 1996, detallando la metodología que seguimos para construirla. Ilustramos aquí su utilidad llevando a cabo un análisis estructural
Gaspar Núñez, Clemente Polo
doaj  

Dirigible Pony Blimb D57

, 2014
Dirigible "Pony Blimb D57" flying over water casting a shadow. Image displayed (72 dpi JPEG), Master image (600 dpi TIFF)

core