Results 21 to 30 of about 1,045 (146)

Room‐temperature crystal structure of a metal‐dependent W‐formate dehydrogenase by serial synchrotron crystallography

open access: yesActa Crystallographica Section D, EarlyView.
We report a room‐temperature serial synchrotron X‐ray crystallographic structural analysis of Nitratidesulfovibrio vulgaris formate dehydrogenase AB, an enzyme that reduces CO2 to formate.Metal‐dependent formate dehydrogenases (Fdhs) are a promising research target in efforts to mitigate climate change by developing active, efficient, selective and ...
Guilherme Vilela-Alves   +7 more
wiley   +1 more source

Endowment Effect, Information Asymmetry, and Real Estate Market Decisions: Willingness to Pay and Willingness to Accept Disparities

open access: yesReal Estate Management and Valuation
The endowment effect has gained dominance over the decades due to its ability to explain behavioral instincts portrayed by individuals when making decisions and its inconsistency with standard economic theories.
Mwanyepedza Robert, Mishi Syden
doaj   +1 more source

Avoiding pitfalls when modelling ligands in macromolecular crystallography

open access: yesActa Crystallographica Section D, EarlyView.
Flawed protein–ligand X‐ray structures can misdirect drug discovery based on PDB‐deposited models. This review uses publicly available PDB examples to highlight potential pitfalls, from absent ligands to incorrect chemistry, and presents a practical validation approach to improve model reliability.The determination of protein–ligand complex structures ...
Oliver S. Smart   +4 more
wiley   +1 more source

Direct deposition on pre‐cooled grids: a new approach to sub‐millisecond cryoEM grid preparation

open access: yesActa Crystallographica Section D, EarlyView.
We describe a new method to prepare grids for cryoEM on the sub‐millisecond timescale.There has been a rapid expansion in new approaches to sample preparation for single‐particle cryoEM. One drive has been around speeding up the process both for the application of time‐resolved studies and in outrunning some of the negative effects which may come from ...
David P. Klebl   +5 more
wiley   +1 more source

Information asymmetries in intrafamily business succession

open access: yesBusiness Research Quarterly, 2022
The often long-lasting process of intrafamily business succession involves contracts for management and ownership transfer that unfold in a complex series of stages.
Sven Wolff, Sabrina Schell, Petra Moog
doaj   +1 more source

Towards routine accurate electron‐density studies of biological macromolecules

open access: yesActa Crystallographica Section D, EarlyView.
Here, we describe the determination of the highest resolution structure in the PDB at 0.43 Å resolution. Electron‐density maps reveal extensive deformation electron density that is completely accounted for by performing transferable aspherical atom refinements using the DiSCaMB library in BUSTER.We report here the structure of Pyrococcus abyssi ...
Elham Paknia   +10 more
wiley   +1 more source

Are Hedonic Models Really Quality-Adjusted? The Role of Apartment Quality in Hedonic Models of Housing Rental Market

open access: yesReal Estate Management and Valuation
In micro-level data concerning the housing market, the apartment quality may be signaled via textual statements or the attached descriptions/photos. It may be done using hard information related to the easier-to-measure structural characteristics or soft
Hebdzyński Michał
doaj   +1 more source

Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor

open access: yesBiochemistry and Biophysics Reports, 2018
Acidic human fibroblast growth factor (hFGF1) plays a key role in cell growth and proliferation. Activation of the cell surface FGF receptor is believed to involve the glycosaminoglycan, heparin.
Julie Eberle Davis   +7 more
doaj   +1 more source

Achieving useful data analytics for marketing: Discrepancies in information quality for producers and users of information

open access: yesBusiness Research Quarterly, 2023
This study proposes as a key cause of the high failure rates in the implementation of analytical projects for marketing decisions, the discrepancy in the information quality (DIQ) perceived between producers (information technology [IT]) and users ...
Manuel Morales-Serazzi   +2 more
doaj   +1 more source

Experimental estimation of copper‐site geometry reproducibility in biologically relevant redox and saccharide‐bound states of a model lytic polysaccharide monooxygenase

open access: yesActa Crystallographica Section D, Volume 82, Issue 8, Page 886-899, August 2026.
Small but measurable changes in the coordination geometry of a lytic polysaccharide monooxygenase copper active site are revealed by X‐ray crystallography, providing structural insight into their catalytic flexibility.Lytic polysaccharide monooxygenases (LPMOs) are copper‐dependent enzymes classified into the auxiliary activity (AA) families of the ...
Zhiyu Huang   +7 more
wiley   +1 more source

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