Results 151 to 160 of about 24,783,297 (283)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Tractor Testing; Belt Power Test; Massey Harris
, 1948 "Test no. 401. Massey-Harris Pony. R. Valentine, H. Hartz, E. Dahl (factory representative), H. Mizner, V. Hitt." They are standing behind the Massey-Harris Pony tractor inside the tractor test lab.
Nebraska Tractor Test Laboratory
core +1 more source
Tractor Testing; Drawbar; Caterpillar
, 1956 "Caterpillar D-9 tested in July and August 1956." Caterpillar D-9 crawler during the drawbar test on the dirt test track, towing two other crawlers, the test car, and three other load ...
Nebraska Tractor Test Laboratory
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Development and Evaluation of a Smartphone App-Based Rapid 25-Hydroxy Vitamin D Test. [PDF]
Diagnostics (Basel)Han S +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Tractor Testing; Belt Test; Allis Chalmers
, 1948 Official belt test no. 397 Allis-Chalmers HD19." The Allis-Chalmers HD-19 crawler on berlt power test inside the tractor test lab. Technician Joe Flamm stands measuring belt speed with a hand-held tachometer.
Nebraska Tractor Test Laboratory
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 1920 "Test #1-Waterloo Boy-1920, Forerunner to Model D John Deere." A rear three-quarter view of the Waterloo Boy tractor being tested inside a building.
Nebraska Tractor Test Laboratory
core