Results 111 to 120 of about 23,467,166 (293)

REPRESENTATION OF VALUE AND SALIENCE IN THE PRIMATE BRAIN [PDF]

, 2015
Most times, we choose goods and avoid evils. Sometimes, goods and evils choose us, which quickly grabs our attention. How do our brains represent our values so that we can choose? How do things we love or loathe automatically capture our attention?
LEATHERS, MARVIN L, LEATHERS, MARVIN/L
core  

Perspectives of clinical stakeholders and patients from four VA liver clinics to tailor practice facilitation for implementing evidence-based alcohol-related care

Addiction Science & Clinical Practice
Background Unhealthy alcohol use (UAU) is particularly dangerous for people with chronic liver disease. Liver clinics may be an important setting in which to provide effective alcohol-related care by integrating evidence-based strategies, such as brief ...
Elena M. Soyer, Madeline C. Frost, Olivia V. Fletcher, George N. Ioannou, Judith I. Tsui, E. Jennifer Edelman, Bryan J. Weiner, Rachel L. Bachrach, Jessica A. Chen, Emily C. Williams   +9 more
doaj   +1 more source

On Causal Inferences for Personalized Medicine: How Hidden Causal Assumptions Led to Erroneous Causal Claims About the D-Value. [PDF]

Am Stat, 2020
Greenland S, Fay MP, Brittain EH, Shih JH, Follmann DA, Gabriel EE, Robins JM.   +6 more
europepmc   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

The Value of Failures in Pharmaceutical R&D [PDF]

We build a cumulative innovation model in which both success and failure provide valuable information for future research. To test this learning mechanism, we use a dataset covering outcomes of world-wide R&D projects in the pharmaceutical industry, and ...
Fabio Pammolli, Massimo Riccaboni, Jing-Yuan Chio, Laura Magazzini   +3 more
core  

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Investment, R&D and liquidity constraints [PDF]

In this contribution, we present a novel instrument to control for investment opportunities in studying the investment-cash-flow sensitivity. More in particular we introduce the book value of R&D.
Pr. D. Patrick Van Cayseele
core  

Valuing the Historic Environment: a critical review of existing approaches to social value [PDF]

, 2015
Through a critical review of existing research, this report examines current knowledge and understanding of social value. Encompassing the significance of the historic environment to contemporary communities, social value relates to people’s sense ...
Jones, Sian, Leech, Steven, Leech, S., Jones, S.   +3 more
core  

Patient-Reported Health-Related Quality of Life Impact and Symptom Severity in Patients with Lyme Borreliosis in the Burden of Lyme Disease (BOLD) Study

Pathogens
Lyme borreliosis (LB) can manifest as a localized infection or, if left untreated, disseminated disease. This analysis used Patient-Reported Outcome tools to assess general health, fatigue, pain, and cognitive function in patients with localized or ...
Holly Yu, Amanda R. Mercadante, Kate Halsby, Alexandra Loew-Baselli, Ye Tan, Juanita Edwards, Frederick J. Angulo, Elizabeth Begier, Mendwas Dzingina, Johan S. Berglund, Anna Moniuszko-Malinowska, Franc Strle, James H. Stark, on behalf of the BOLD Study Group   +13 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source