Results 41 to 50 of about 50,976 (267)

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

open access: yesAdvanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang   +7 more
wiley   +1 more source

Impact of direct-acting antiviral therapy for hepatitis C-related hepatocellular carcinoma.

open access: yesPLoS ONE, 2020
With the introduction of direct-acting antiviral (DAA) agents, hepatitis C virus (HCV) treatment has dramatically improved. However, there are insufficient data on the benefits of DAA therapy in hepatocellular carcinoma (HCC).
Wei-Chen Lin   +6 more
doaj   +1 more source

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo   +23 more
wiley   +1 more source

Decreased Incidence of Hepatocellular Carcinoma after Directly Acting Antiviral Therapy in Patients with Hepatitis C–Related Advanced Fibrosis and Cirrhosis

open access: yesJournal of Hepatocellular Carcinoma, 2021
Shimaa Kilany,1 Lmyaa Ata,1 Asmaa Gomaa,1 Aliaa Sabry,1 Ali Nada,1 El-Sayed Tharwa,1 Gamal Badra,1 Ashraf Abogabal,1 Mohamed Elwaraky,2 Enas Moaz,3 Sameera Ezzat,3 Ahmed Elsharawy,4 Imam Waked1 1Hepatology and Gastroenterology Department, National Liver ...
Kilany S   +12 more
doaj  

Exchanging Data Agreements in the DaaS Model [PDF]

open access: yes2011 IEEE Asia-Pacific Services Computing Conference, 2011
Rich types of data offered by data as a service(DaaS) in the cloud are typically associated with different and complex data concerns that DaaS service providers, data providers and data consumers must carefully examine and agree with before passing and utilizing data.
Hong Linh Truong 0001   +7 more
openaire   +1 more source

Defining the Collision Avoidance Region for DAA Systems [PDF]

open access: yes, 2016
Unmanned aircraft systems (UAS) will be required to equip with a detect-and-avoid (DAA) system in order to satisfy the federal aviation regulations to maintain well clear of other aircraft, some of which may be equipped with a Traffic Collision Avoidance
Park, Chunki   +4 more
core  

Multiscale Modeling of an 8‐Week Combination Regimen of Bemnifosbuvir and Ruzasvir in Patients with Chronic Hepatitis C Virus Infection

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Bemnifosbuvir (BEM) and ruzasvir (RZR) are pan‐genotypic HCV polymerase (NS5B) and NS5A inhibitors, respectively. In a single‐arm study (NCT05904470), 215 treatment‐naïve, adherent participants with chronic HCV (with or without cirrhosis) received BEM 550 mg QD plus RZR 180 mg QD for 8 weeks.
Carolin Zitzmann   +4 more
wiley   +1 more source

AIAA Aviation UAS DAA Demonstration-Mini HITL Week 2 Stats [PDF]

open access: yes, 2016
The UAS-NAS Project demo will showcase recent research efforts to ensure the interoperability between proposed UAS detect and avoid (DAA) human machine interface requirements (developed within RTCA SC-228) and existing collision avoidance displays ...
Fern, Lisa Carolynn   +2 more
core  

Multidimensional Engineering Enabling Rate‐Matched C−N Coupling for Efficient Organonitrogen Electrosynthesis

open access: yesEcoEnergy, EarlyView.
This review introduces rate matching as a unifying design principle for efficient electrochemical C−N coupling and highlights multidimensional engineering of catalysts, interfaces, and reactors to synchronize the generation of carbon‐ and nitrogen‐containing intermediates, balance their surface coverages, maximize C−N bond formation, and enable ...
Kaixing Cai   +4 more
wiley   +1 more source

A DAA Scheme Requiring Less TPM Resources [PDF]

open access: yes, 2010
Direct anonymous attestation (DAA) is a special digital signature primitive, which provides a balance between signer authentication and privacy. One of the most interesting properties that makes this primitive attractive in practice is its construction ...
Liqun Chen
core   +1 more source

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