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Amino acid storage: lysosomal double role in health and disease
Autophagy ReportsCellular homeostasis depends on a multitude of cellular functions, which in turn depend on the clearance of damaged components for their maintenance.
Aiswarya Raj +2 more
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Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid [PDF]
Nature Communications, 2017 Non-proteinogenic (np) amino acids in the food chain present challenges for the human translation machinery. Here the authors show that, while AlaRS and ProRS activate toxic np azetidine-2-carboxylic acid (Aze) present in sugar beets and lilies, only the
Youngzee Song +10 more
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Leucyl-tRNA synthetase: double duty in amino acid sensing [PDF]
Cell Research, 2012 The cellular response to amino acids is controlled at the molecular level by TORC1. While many of the elements that participate in TORC1 signaling are known, we still have no clear idea how cells sense amino acids. Two recent studies found that leucyl-tRNA synthetase (LRS) is a leucine sensor for TORC1, in both yeast and mammalian cells.
Durán, R. V., Hall, M. N.
openaire +4 more sources
Walailak Journal of Science and Technology, 2021 Intercalation of 4-amino benzoic acid (4-AB) into Zn/Al-nitrate layered double hydroxide (ZAL2) to form Zn/Al-4AB (ZALAB) compound was successfully synthesized from nitrate salt by using direct co-precipitation method.
Fadhlin Sakina MOHD RAJIDI +3 more
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Agronomy, 2023 Soil extracellular enzyme activities play an important role in regulating the soil nitrogen (N) mineralization process in paddy fields. However, there is still a need to further study how N mineralization responds to different fertilizer management ...
Haiming Tang +6 more
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Frontiers in Microbiology, 2021 Asperphenamate is a small peptide natural product that has gained much interest due to its antitumor activity. In the recent years numerous bioactive synthetic asperphenamate analogs have been reported, whereas only a handful of natural analogs either of
Karolina Subko +10 more
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A Healthy and Ecologically Balanced Environment: An Argument for a Third Generation Right [PDF]
, 1993 Chymotrypsin-like serine proteases are found in high abundance in mast cell granules. By site-directed mutatgenesis, we have previously shown that basic amino acids in positions 143 and 192 (Arg and Lys respectively) of the human mast cell chymase are ...
Ahooghalandari, Parvin +5 more
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Chiral Recognition by DNA-Immobilized TLC Plate
Separations, 2017 DNA-immobilized silica gel TLC plate (DNA-TLC plate) by coating a mixture of double-stranded DNA and silica gel on a glass plate was stable in common organic solvents, such as alcohol, acetone, chloroform, and ethyl acetate.
Masanori Yamada, Mami Inoue
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Frontiers in Chemistry, 2022 We presented a facile and scalable route for the synthesis of di-azido sugars via one-pot double inversion of the mono-benzoyl sugars by TBAN3 and studied the dependency pattern between solvent and protecting groups as well as the configuration of the ...
Yixuan Zhou +3 more
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l-Amino Acid Production by a Immobilized Double-Racemase Hydantoinase Process: Improvement and Comparison with a Free Protein System [PDF]
, 2017 Protein immobilization is proving to be an environmentally friendly strategy for manufacturing biochemicals at high yields and low production costs. This work describes the optimization of the so-called “double-racemase hydantoinase process,” a system of
Clemente Jiménez, María José +3 more
core +3 more sources