Results 21 to 30 of about 1,052,978 (300)

Point mutations of the P53 gene, human hepatocellular carcinoma and aflatoxins [PDF]

, 1993
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inactivation by allelic deletions or point mutations within the P53 gene as well as complex formation of wildtype p53 with cellular or viral proteins is a ...
Alexander L. Gerbes, Aoyama, Barak, Bressac, Bressac, Buetow, Caselmann, Challen, Colombo, Donehower, Fields, Finlay, Foster, Halevy, Hsu, Jenkins, Kastan, Kekulé, Kew, Kress, Lane, Laurent-Puig, Lilleberg, Livingstone, Ludlow, Malkin, Marshall, Meyer, Meyer, Mueller, Murakami, Nigro, Ozturk, Raycroft, Sarnow, Slagle, Srivastava, Sturzbecher, Taylor, Wolfgang H. Caselmann, Wollersheim   +40 more
core   +1 more source

Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirus

Retrovirology, 2005
Background Infection by jaagsiekte sheep retrovirus (JSRV) and by enzootic nasal tumor virus (ENTV) depends on cell-surface expression of the virus entry receptor, hyaluronidase 2 (Hyal2).
Dirks Clarissa, Duh Fuh-Mei, Lerman Michael I, Miller A Dusty   +3 more
doaj   +1 more source

Evolution of the eyes of vipers with and without infrared-sensing pit organs [PDF]

, 2019
We examined lens and brille transmittance, photoreceptors, visual pigments, and visual opsin gene sequences of viperid snakes with and without infrared-sensing pit organs. Ocular media transmittance is high in both groups.
Douglas, R. H., Gower, D. J., Grace, M. S., Hart, N. S., Hunt, D. M., Loew, E. R., McLamb, W., Orlov, N., Partridge, J. C., Peichl, L., Sampaio, F. L., Simoes, B. F., Wagner, H. J.   +12 more
core   +3 more sources

Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling.

PLoS ONE, 2019
Cryptococcosis is an Invasive Fungal Infection (IFI) caused by Cryptococcus neoformans, mainly in immunocompromised patients. Therapeutic failure due to pathogen drug resistance, treatment inconstancy and few antifungal options is a problem. The study of
Crislaine Lambiase Calvete, Kevin Felipe Martho, Gabrielle Felizardo, Alexandre Paes, João Miguel Nunes, Camila Oliveira Ferreira, Marcelo A Vallim, Renata C Pascon   +7 more
doaj   +1 more source

Amino Acid Permeases and Virulence in Cryptococcus neoformans. [PDF]

PLoS ONE, 2016
Fungal opportunistic pathogens colonize various environments, from plants and wood to human and animal tissue. Regarding human pathogens, one great challenge during contrasting niche occupation is the adaptation to different conditions, such as ...
Kevin Felipe Cruz Martho, Amanda Teixeira de Melo, Juliana Possato Fernandes Takahashi, Juliana Mariotti Guerra, Dayane Cristina da Silva Santos, Sônia Ueda Purisco, Márcia de Souza Carvalho Melhem, Raquel Dos Anjos Fazioli, Clerlune Phanord, Patrícia Sartorelli, Marcelo A Vallim, Renata C Pascon   +11 more
doaj   +1 more source

Comparative analysis of casein complex and amino acid composition in single-humped and double-humped camel milk: Implications for dairy camel breeding [PDF]

Caspian Journal of Environmental Sciences, 2023
The purpose of this work is to study the casein complex of camel milk and their amino acid composition. including the chemical composition and physico-chemical properties of milk of single-humped and double-humped camels, as well as the fractional ...
Kuanysh Syman, Raissa Utegaliyeva, Abdreshov Serik Nauryzbaevish, Zharylkassynova Zhazira, Aytzhanova Mira Onlanbekovna, Kalekeshov Askar Maralovich, Mamataeva Aigul Tumaevna   +6 more
doaj   +1 more source

Formation and structure of the ferryl [Fe=O] in-termediate in the non-haem iron halogenase SyrB2: classical and QM/MM modelling agree [PDF]

, 2017
To rationalise mechanistically the intriguing regio- and chemoselectivity patterns for different substrates of the non-haem iron/2-oxoglutarate dependent halogenase SyrB2, it is crucial to elucidate the structure of the pivotal [FeIV[double bond, length ...
Rugg, G., Senn, H.M.
core   +1 more source

Randomized double-blind trial of oral essential amino acids for dialysis-associated hypoalbuminemia [PDF]

Kidney International, 2000
Hypoalbuminemia is associated with substantial morbidity and mortality in dialysis patients.Subjects with a mean three-month prestudy serum albumin of 3.8 g/dL or less and who demonstrated >/=90% compliance during a two-week run-in period were randomized to 3.6 g of essential amino acids (EAAs) or placebo three times daily with meals for three months ...
Eustace, Joseph A., Coresh, Josef, Kutchey, Chris, Te, Purita L., Gimenez, Luis F., Scheel, Paul J., Walser, Mackenzie   +6 more
openaire   +2 more sources

2-Phenyl-tetrahydropyrimidine-4(1H)-ones – cyclic benzaldehyde aminals as precursors for functionalised β2-amino acids

Beilstein Journal of Organic Chemistry, 2009
Novel procedures have been developed to condense benzaldehyde effectively with β-amino acid amides to cyclic benzyl aminals. Double carbamate protection of the heterocycle resulted in fully protected chiral β-alanine derivatives. These serve as universal
Markus Nahrwold, Arvydas Stončius, Anna Penner, Beate Neumann, Hans-Georg Stammler, Norbert Sewald   +5 more
doaj   +1 more source

Improved screening procedure for biogenic amine production by lactic acid bacteria and Enterobacteria

Czech Journal of Food Sciences, 2015
An improved screening procedure was developed for the detection of amino acid decarboxylase-positive microorganisms (especially lactic acid bacteria and Enterobacteria).
Lu SHILING, Jiang CAIHONG, Xu XINGLIAN, Xu CHENGJIAN, Li KAIXIONG, Shu RUIHUA   +5 more
doaj   +1 more source