Results 31 to 40 of about 1,052,978 (300)
Effects of Low Temperature on the Amino Acid Composition of Wheat Grains
Agronomy, 2022 Global warming can have detrimental effects on crop production formation, but the effect of low-temperature stress on crop quality should not be ignored.
Xinyi Hu +9 more
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Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]
, 2009 Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core +2 more sources
Reliable prediction of protein thermostability change upon double mutation from amino acid sequence [PDF]
Bioinformatics, 2009 Abstract Summary: The accurate prediction of protein stability change upon mutation is one of the important issues for protein design. In this work, we have focused on the stability change of double mutations and systematically analyzed the wild-type and mutant residues, patterns in amino acid sequence and locations of mutants.
Liang-Tsung, Huang, M Michael, Gromiha
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PLoS ONE, 2017 Canonical processing of miRNA begins in the nucleus with the Microprocessor complex, which is minimally composed of the RNase III enzyme Drosha and two copies of its cofactor protein DGCR8.
Joshua C Kranick +3 more
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The importance of cache domains in α2δ proteins and the basis for their gabapentinoid selectivity
Channels, 2023 In this hybrid review, we have first collected and reviewed available information on the structure and function of the enigmatic cache domains in α2δ proteins.
Karen M Page +4 more
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Genomics and proteomics: a signal processor's tour [PDF]
, 2004 The theory and methods of signal processing are becoming increasingly important in molecular biology. Digital filtering techniques, transform domain methods, and Markov models have played important roles in gene identification, biological sequence ...
Vaidyanathan, P. P.
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Probing RNA recognition by human ADAR2 using a high-throughput mutagenesis method. [PDF]
, 2016 Adenosine deamination is one of the most prevalent post-transcriptional modifications in mRNA. In humans, ADAR1 and ADAR2 catalyze this modification and their malfunction correlates with disease. Recently our laboratory reported crystal structures of the
Beal, Peter A, Wang, Yuru
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Microbial Cell Factories, 2021 Background d-Amino acids are increasingly used as building blocks to produce pharmaceuticals and fine chemicals. However, establishing a universal biocatalyst for the general synthesis of d-amino acids from cheap and readily available precursors with few
Dan-Ping Zhang +5 more
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Evolutionary Covariant Positions within Calmodulin EF-hand Sequences Promote Ligand Binding [PDF]
, 2018 Intracellular calcium signaling is an essential regulatory mechanism through calcium-mediated signal transduction pathways involved in many cell processes, such as exocytosis, motility, apoptosis, excitability, transcription, and muscle contraction.
Vaidyanathan, Uma
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The physical characteristics of human proteins in different biological functions. [PDF]
PLoS ONE, 2017 The physical properties of gene products are the foundation of their biological functions. In this study, we systematically explored relationships between physical properties and biological functions.
Tengjiao Wang, Hailin Tang
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