Results 41 to 50 of about 340,341 (299)

Different purpose design strategies and techniques to improve the performance of a dual active bridge with phase-shift control [PDF]

open access: yes, 2015
This paper addresses the performance of the bidirectional dual active bridge (DAB) converter. One of the advantages of the DAB is the possibility to achieve the zero-voltage switching (ZVS) operation in all the switches of this converter.
González Lamar, Diego   +4 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Fuzzy Logic Control of Adaptive ARQ for Video Distribution over a Bluetooth Wireless Link [PDF]

open access: yes, 2007
Bluetooth's default automatic repeat request (ARQ) scheme is not suited to video distribution resulting in missed display and decoded deadlines. Adaptive ARQ with active discard of expired packets from the send buffer is an alternative approach. However,
Fleury, M, Ghanbari, M, Razavi, R
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Molecular and Mechanistic Characterization of PddB, the First PLP-Independent 2,4-Diaminobutyric Acid Racemase Discovered in an Actinobacterial D-Amino Acid Homopolymer Biosynthesis

open access: yesFrontiers in Microbiology, 2021
We recently disclosed that the biosynthesis of antiviral γ-poly-D-2,4-diaminobutyric acid (poly-D-Dab) in Streptoalloteichus hindustanus involves an unprecedented cofactor independent stereoinversion of Dab catalyzed by PddB, which shows weak homology to
Kazuya Yamanaka   +5 more
doaj   +1 more source

Operating Principle and Performance Optimization of a Three-Level NPC Dual-Active-Bridge DC-DC Converter [PDF]

open access: yes, 2015
© 1982-2012 IEEE. Aiming to improve the performance features of conventional two-level dual-active-bridge (DAB) converters, this paper presents a three-level neutral-point-clamped (NPC) DAB dc-dc converter.
Bordonau Farrerons, José   +3 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer

open access: yesCells, 2019
Background: Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to standard chemo- and radiotherapy. Recently, a new class of non-platinum-based halogenated molecules (called FMD compounds) was discovered that selectively kills cancer cells. Here,
Robert G. Goetze   +10 more
doaj   +1 more source

A Bidirectional Soft-Switched DAB-Based Single-Stage Three-Phase AC–DC Converter for V2G Application [PDF]

open access: yes, 2019
In vehicle-to-grid applications, the battery charger of the electric vehicle (EV) needs to have a bidirectional power flow capability. Galvanic isolation is necessary for safety.
Baranwal, Rohit   +4 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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