Results 41 to 50 of about 178,490 (300)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Kinetic approach to evaluate the effects of 3,3'-diaminobenzidine on N mineralization in soils
Plant, Soil and Environment, 2010 It has been demonstrated that azo dyes, the xenobiotics widely use in industries, can pose threats to public health. 3,3'-diaminobenzidine (DAB), as a benzidine analogue, is generated from reduction of azo dyes by intestinal or environmental ...
B. Jalili, F. Nourbakhsh, M. Ghiasi
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Diskreta ljud: om DAB som radio
MedieKultur: Journal of Media and Communication Research, 2001 Er DAB (Digital Audio Broadcast) den revolution af radiomediet som det ofte er blevet påstået? I sin analyse af DAB forholder Carin Åberg sig kritisk til den måde DAB og det europæiske forskningsprojekt i di- gital distributionsteknik EUREKA-147 har
Carin Åberg
doaj +3 more sources
The Invisible Behmoth: The Moral Legacy of the Cold War
New Proposals, 2008 A comment on the moral outcome of the cold war.
Dennis Alan Bartels
doaj
Nature Communications, 2023 The type of reactions and the availability of monomers for the synthesis of sp 2 -c linked covalent organic frameworks (COFs) are considerably limited by the irreversibility of the C=C bond.
Cheng-Peng Niu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The Journal of Engineering, 2019 A design procedure for the dual active bridge (DAB) converter is presented, which aims to optimised power density and computational effort. When designing a DAB, the selection of circuit design parameters such as switching frequency, leakage inductance ...
Niklas Fritz +4 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source