Results 51 to 60 of about 340,341 (299)
From Handmills to Windmills: Technology Gatekeeping in Medieval Europe and Contemporary Ontario
New Proposals, 2012 A commentary on the power of propertied classes and labour aristocracies in relation to the propagation of sustainable energy.
Dennis Alan Bartels
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Invisible Behmoth: The Moral Legacy of the Cold War
New Proposals, 2008 A comment on the moral outcome of the cold war.
Dennis Alan Bartels
doaj
Kinetic approach to evaluate the effects of 3,3'-diaminobenzidine on N mineralization in soils
Plant, Soil and Environment, 2010 It has been demonstrated that azo dyes, the xenobiotics widely use in industries, can pose threats to public health. 3,3'-diaminobenzidine (DAB), as a benzidine analogue, is generated from reduction of azo dyes by intestinal or environmental ...
B. Jalili, F. Nourbakhsh, M. Ghiasi
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Diskreta ljud: om DAB som radio
MedieKultur: Journal of Media and Communication Research, 2001 Er DAB (Digital Audio Broadcast) den revolution af radiomediet som det ofte er blevet påstået? I sin analyse af DAB forholder Carin Åberg sig kritisk til den måde DAB og det europæiske forskningsprojekt i di- gital distributionsteknik EUREKA-147 har
Carin Åberg
doaj +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Nature Communications, 2023 The type of reactions and the availability of monomers for the synthesis of sp 2 -c linked covalent organic frameworks (COFs) are considerably limited by the irreversibility of the C=C bond.
Cheng-Peng Niu +4 more
doaj +1 more source
Reliable Download Delivery in a Terrestrial DAB Network [PDF]
, 2008 Reliable file transfer is important in broadcast networks. In this paper, we have investigated if it is useful to extend the DAB standard with Fountain codes. To evaluate this, results from measurements in a live Single Frequency Network (SFN) were used.
Schiphorst, R., Shao, X., Slump, C.H.
core +1 more source