Advanced Science, EarlyView.The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Optimized coil arrangement for integrating leakage inductance in high-frequency transformers of dual active bridge converters. [PDF]
Sci RepYadollahi K, Zakipour A.
europepmc +1 more source
High Frequency AC Inductor Analysis and Design for Dual Active Bridge (DAB) Converters [PDF]
, 2016 Andersen, Michael A. E., Zhang, Zhe
core +1 more source
Evaluation of isolated DCDC converter topologies for future HVDC aerospace microgrids [PDF]
High performance power conversion equipment is currently gaining an increasing interest for aircraft applications. In particular, isolated bidirectional DC/DC converters are often proposed for modern HVDC aircraft distribution systems. For such reason an
Costabeber, Alessando +4 more
core
Advanced Science, EarlyView.Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao +25 more
wiley +1 more source
Hardware-in-loop implementation of an adaptive MPPT controlled PV-assisted EV charging system with vehicle-to-grid integration. [PDF]
Sci RepSingh S, Bansal HO.
europepmc +1 more source
GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis
Advanced Science, EarlyView.This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang +9 more
wiley +1 more source
Performance evaluation of a series-connected step-up/down partial power converter for battery energy storage applications. [PDF]
Sci RepLiu Q +6 more
europepmc +1 more source
Advanced Science, EarlyView.This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo +11 more
wiley +1 more source
Transient current balancing modulation for seamless load step response in a dual-active-bridge converter with triple phase-shift control. [PDF]
Sci RepZhou S, Tang J.
europepmc +1 more source