Results 51 to 60 of about 8,156 (311)

Design and evaluation of a reconfigurable stacked active bridge dc/dc converter for efficient wide load-range operation [PDF]

open access: yes, 2017
This paper presents the design and implementation of a large-step-down soft-switched dc-dc converter based on the active bridge technique which overcomes some of the limitations of the conventional Dual Active Bridge (DAB) converter.
Abramson, Rose A.   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Control Strategies for the DAB Based PV Interface System. [PDF]

open access: yesPLoS ONE, 2016
This paper presents an interface system based on the Dual Active Bridge (DAB) converter for Photovoltaic (PV) arrays. Two control strategies are proposed for the DAB converter to harvest the maximum power from the PV array. The first strategy is based on
Hadi M El-Helw   +2 more
doaj   +1 more source

Hybrid and modular multilevel converter designs for isolated HVDC–DC converters [PDF]

open access: yes, 2018
Efficient medium and high-voltage dc-dc conversion is critical for future dc grids. This paper proposes a hybrid multilevel dc-ac converter structure that is used as the kernel of dc-dc conversion systems.
Adam, G.P.   +4 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Extended ZVS-On/ZCS-Off Range for CF-DAB Converter Under DCM Operation for Residential Energy Storage Systems

open access: yesIEEE Access, 2023
Current-Fed Dual-Active Bridge (CF-DAB) converters are interesting in bidirectional applications when a wide conversion voltage ratio is required, such as residential extra-low voltage energy storage systems, where conventional DAB converters have ...
Edivan Laercio Carvalho   +6 more
doaj   +1 more source

Cost-Effective and High-Efficiency Variable-Speed Switched Reluctance Drives With Ring-Connected Winding Configuration [PDF]

open access: yes, 2019
This paper presents a novel converter topology for six-phase switched reluctance motor (SRM) drives, which reduces the number of switches and diodes by half, compared with the conventional asymmetric half-bridge converter, but needs no additional energy ...
Deng, Xu   +4 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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