Results 21 to 30 of about 3,304 (223)

Serum Cholesterol Concentration on Admission in 415 Dogs Envenomated by Daboia (Vipera) palaestinae as a Marker of Envenomation Severity and Outcome-A Retrospective Study. [PDF]

Toxins (Basel), 2023
Daboia (Vipera) palaestinae (Dp), accounts for most envenomations in humans and dogs in Israel. In humans envenomed by Dp, serum cholesterol concentration (sChol) is inversely correlated with envenomation severity.
Klainbart S, Kelmer E, Beeri-Cohen I, Keinan Y, Segev G, Aroch I.   +5 more
europepmc   +2 more sources

Clinical and laboratory features distinguishing between Deinagkistrodon acutus and Daboia siamensis envenomation [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background There are 6 species of venomous snakes in Taiwan. Two of them, Deinagkistrodon acutus (D. acutus) and Daboia siamensis (D. siamensis), can cause significant coagulopathy.
Hung-Yuan Su, Shih-Wei Huang, Yan-Chiao Mao, Ming-Wen Liu, Kuo-Hsin Lee, Pei-Fang Lai, Ming-Jen Tsai   +6 more
doaj   +4 more sources

Neutralization of systemic toxicity of Daboia russelii venom and reprotoxin fraction by IgY antibodies

Medicine in Drug Discovery
Daboia russelii, a highly venomous snake prevalent in South Asia, causes significant morbidity and mortality due to its complex venom, which includes neurotoxins, hemotoxins, and reprotoxins.
Punithkumar Naraganahalli Krishnaraj, Kiran Kumar Mudnakudu-Nagaraju, Nagalambika Prasad, Chandavi Venkatesh, Deekshith Ramesh, Druthi Venktesh, Anusha Chikkamandagere Kumar, Kumar Jajur Ramanna   +7 more
doaj   +2 more sources

Acute phase reactions in Daboia siamensis venom and fraction-induced acute kidney injury: the role of oxidative stress and inflammatory pathways in in vivo rabbit and ex vivo rabbit kidney models [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: This study examines the direct nephrotoxic effects of Daboia siamensis venom (RVV) and venom fractions in in vivo and isolated perfused kidneys (IPK) to understand the role of inflammation pathways and susceptibility to oxidative stress in ...
Narongsak Chaiyabutr, Jureeporn Noiprom, Kanyanat Promruangreang, Taksa Vasaruchapong, Panithi Laoungbua, Orawan Khow, Lawan Chanhome, Visith Sitprija   +7 more
doaj   +2 more sources

Single Chain Antibody Fragment against Venom from the Snake Daboia russelii formosensis [PDF]

Toxins, 2017
Russell’s vipers containing hemotoxic and neurotoxic venom commonly cause snake envenomation. Horse-derived antivenom is a specific antidote, but its production is expensive and has side effects. Developing a cost-effective and more tolerable therapeutic
Chi-Hsin Lee, Yu-Ching Lee, Yueh-Lun Lee, Sy-Jye Leu, Liang-Tzung Lin, Chi-Ching Chen, Jen-Ron Chiang, Pharaoh Fellow Mwale, Bor-Yu Tsai, Ching-Sheng Hung, Yi-Yuan Yang   +10 more
doaj   +3 more sources

Neutrophil-mediated erythrophagocytosis following Russell's viper (Daboia russelii) bite.

Toxicon, 2023
Snakebite envenomation is regarded as a high-priority neglected tropical disease by the World Health Organisation, as it results in significant loss of lives and permanent disabilities. Russell's viper is one of the important venomous snakes that causes morbidities, mortalities and disabilities in India.
S. Senthilkumaran, S. Arathisenthil, Jarred Williams, J. R. Almeida, Harry F. Williams, E. Rajan, P. Thirumalaikolundusubramanian, Ketan Patel, Sakthivel Vaiyapuri   +8 more
semanticscholar   +3 more sources

Analytical Size Exclusion Chromatography Coupled with Mass Spectrometry in Parallel with High-Throughput Venomics and Bioassaying for Venom Profiling

Toxins, 2023
Modern analytical size exclusion chromatography (SEC) is a suitable technique to separate venom toxin families according to their size characteristics. In this study, a method was developed to separate intact venom toxins from Bungarus multicinctus and ...
Sedef Terzioglu, Mátyás A. Bittenbinder, Julien Slagboom, Bas van de Velde, Nicholas R. Casewell, Jeroen Kool   +5 more
doaj   +1 more source

Comparative Snake Venom Analysis for Facilitating Wildlife Forensics: A Pilot Study

Journal of Analytical Methods in Chemistry, 2022
Confirm and authentic identification of species is required for the implementation of wildlife laws in cases of illegal trafficking of snake venoms. Illegally trafficked snake venom might be misidentified with other drugs of abuse, and sometimes, the ...
Saurabh Bhargava, Kiran Kumari, Rajendra Kumar Sarin, Rajvinder Singh   +3 more
doaj   +1 more source

Capillary leak syndrome due to Russell's viper envenomation—A doomy presage for treating clinician

Journal of Family Medicine and Primary Care, 2022
Russell's viper envenomation is a major challenge to physicians providing intensive care due to diverse presentations and dismal outcomes. The venom can cause idiopathic systemic capillary leak syndrome manifesting with bilateral parotid swelling ...
A S Hariharan, Shivkumar Gopalakrishnan, Bobby Abraham   +2 more
doaj   +1 more source

A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: Application to a dose-finding trial for a novel Russell's viper antivenom in Myanmar.

PLoS Neglected Tropical Diseases, 2020
For most antivenoms there is little information from clinical studies to infer the relationship between dose and efficacy or dose and toxicity. Antivenom dose-finding studies usually recruit too few patients (e.g.
James A Watson, Thomas Lamb, Jane Holmes, David A Warrell, Khin Thida Thwin, Zaw Lynn Aung, Min Zaw Oo, Myat Thet Nwe, Frank Smithuis, Elizabeth A Ashley   +9 more
doaj   +1 more source