Results 21 to 30 of about 5,674 (178)

SARS-CoV-2 Papain-like Protease Responsive ZnO/Daclatasvir-Loaded Chitosan/Gelatin Nanofibers as Smart Antimicrobial Medical Textiles: In Silico, In Vitro and Cell Studies

open access: yesPharmaceutics, 2023
A significant number of deaths are reported annually worldwide due to microbial and viral infections. The development of protective medical textiles for patients and healthcare professionals has attracted many researchers’ attention.
Mohamed Hamdi   +3 more
doaj   +1 more source

Effects of 12-week treatment with Sovodak in patients infected by genotype 1 hepatitis C virus [PDF]

open access: yesJournal of Research in Clinical Medicine, 2019
Introduction: It has been shown that the combination therapy of Sofosbuvir-Daclatasvir (Sof/Dac) has a high rate of success in the treatment of patients. For the first time, a single pill of Sof/Dac has been formulated in Iran (Sovodak).
Hosein Mehdipour   +4 more
doaj   +1 more source

The effectiveness of daclatasvir based therapy in European patients with chronic hepatitis C and advanced liver disease [PDF]

open access: yes, 2017
Background There is limited evidence for the effectiveness of daclatasvir in patients whose hepatitis C threatens their life expectancy.
Weis, Nina   +18 more
core   +4 more sources

Efficacy and safety of narlaprevir/ritonavir and daclatasvir non interferon combination in population of Russian patients with chronic hepatitis C [PDF]

open access: yesТерапевтический архив, 2019
Aim. Evaluate efficacy and safety of a combination of direct - acting antivirals narlaprevir/ritonavir with daclatasvir in patients with viral hepatitis C. Materials and methods.
E A Klimova   +11 more
doaj   +1 more source

Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors

open access: yesViruses, 2022
Chronic hepatitis C virus (HCV) infections are a worldwide medical problem responsible for diverse types of liver diseases. The NS5B polymerase enzyme has become a very interesting target for the development of anti-HCV drugs owing to its fundamental ...
Tamer Nasr   +7 more
doaj   +1 more source

Acute Interstitial Nephritis Associated with Sofosbuvir and Daclatasvir. [PDF]

open access: yes, 2017
Although new heptatis C virus treatments have increased efficacy and improved safety profiles, they also come with risk. We describe a 66-year-old white man with Child-Pugh A cirrhosis secondary to heptatis C virus genotype 3, who suffered from an acute ...
Majoni, William, Ashraf, Taha
core   +2 more sources

Daclatasvir and asunaprevir combination therapy for patients with chronic hepatitis C virus genotype 1b infection in real world [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims Previous studies have reported a high rate of sustained virologic response (SVR) and a low rate of serious adverse events with the use of daclatasvir (DCV) and asunaprevir (ASV) combination therapy. We evaluated the efficacy and safety of
Jae Young Oh   +14 more
doaj   +1 more source

Safety and Efficacy of Sofosbuvir and Daclatasvir in The Treatment of Chronic HCV Infection in Elderly Egyptian Patients [PDF]

open access: yesInternational Journal of Medical Arts, 2021
Background: Chronic Hepatitis-C virus [HCV] infection is endemic in Egypt, with the highest prevalence worldwide. There are few studies on the effectiveness and safety of direct acting antivirals in treating geriatric patients with chronic HCV.
Mohamed G. Mohamed   +3 more
doaj   +1 more source

The impact of sofosbuvir/daclatasvir or ribavirin in patients with severe COVID-19 [PDF]

open access: yes, 2020
OBJECTIVES: Sofosbuvir and daclatasvir are direct-acting antivirals highly effective against hepatitis C virus. There is some in silico and in vitro evidence that suggests these agents may also be effective against SARS-CoV-2.
Mousaviasl, Sajedeh   +21 more
core   +1 more source

Sustained virological response to antiviral drugs in treatment of different genotypes of HCV cirrhotic patients

open access: yesPakistan Journal of Pharmaceutical Sciences, 2023
Cirrhosis and liver cancer are both caused by hepatitis C virus (HCV) infection of the liver. Patients with HCV cirrhosis may be treated with one of many antiviral medications, depending on their specific genotype.
Amin Ullah   +14 more
doaj   +1 more source

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