Results 51 to 60 of about 5,788 (178)

Sex Disparities in Hepatitis C Treatment Initiation: Role of Universal Access to DAA in France (ANRS FANTASIO 2)

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background and Aims Ensuring access to direct‐acting antivirals (DAA) for all individuals concerned is a priority in hepatitis C elimination efforts. We analysed sex disparities in DAA initiation in France over a 9‐year period spanning before and after August 2017, when the country implemented universal DAA access.
Fabienne Marcellin, Clémence Ramier, Cécile Brouard, Vincent Di Beo, Yoann Allier, Abbas Mourad, Morgane Bureau‐Stoltmann, Philippe Sogni, Sylvie Deuffic‐Burban, Patrizia Carrieri, Benjamin Rolland, Marc Bourliere, Camelia Protopopescu   +12 more
wiley   +1 more source

METHOD DEVELOPMENT AND VALIDATION OF ULTRAVIOLET-VISIBLE SPECTROSCOPIC METHOD FOR THE ESTIMATION OF HEPATITIS-C DRUGS - DACLATASVIR AND SOFOSBUVIR IN ACTIVE PHARMACEUTICAL INGREDIENT FORM [PDF]

, 2016
Objective: The objective of the present work is to develop a simple, efficient, and reproducible spectrophotometric method for the quantitativeestimation of hepatitis-C drugs - Daclatasvir and Sofosbuvir in its active pharmaceutical ingredient (API) form.
A, Praveen Kumar, Chakravarthy V, Ashok, Bbv, Sailaja   +2 more
core   +3 more sources

Evaluation of Patients' Recovery from Hepatitis C Following Antiviral Treatment with Daclatasvir and Sofosbuvir in AL-Baha Region [PDF]

International Journal of Advanced Humanities Research
The liver is the largest organ in the body, located below the diaphragm and protected by the lower ribs of the rib cage (Johns Hopkins Medicine, 2022).
Fahad Alghamdi, Rashed Mohammed
doaj   +1 more source

Prenatal testing and postpartum treatment for hepatitis C virus among women with opioid use disorder

Pregnancy, Volume 2, Issue 5, September 2026.
Abstract Introduction In the past decade, hepatitis C virus (HCV) infections among pregnant women increased dramatically in the United States, rising in parallel with the opioid crisis and increasing the number of children at risk for HCV. People with HCV infection that remains untreated are also at increased risk of cirrhosis, liver cancer, and death.
Lucas Gosdin, Kathryn Miele, Shin Y. Kim, Marcela C. Smid, Julie H. Shakib, Judette M. Louis, Tanner Wright, Neil S. Seligman, Carrie Irvine, Pilar M. Sanjuan, Lawrence Leeman, Michelle L. Henninger, Autumn Davidson, Elisha M. Wachman, Kara M. Rood, Anna Bartholomew, Suzanne Gilboa, Kate R. Woodworth, Van T. Tong, Lakshmi Panagiotakopoulos   +19 more
wiley   +1 more source

Boletín CIME 02 : Daclatasvir [PDF]

, 2016
Publicaciones CIMEFil: Sola, Nancy. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina.Este Boletín está estructurado con una introducción general del ingrediente farmacéutico activo daclatasvir, su aprobación en Argentina y la ...
Sola, Nancy
core  

RAS in NS3 and NS5A regions after failure of daclatasvir/asenaprevir combination therapy.

, 2016
RAS in NS3 and NS5A regions after failure of daclatasvir/asenaprevir combination therapy.
Miyako Murakawa (3239484), Takehiko Abe (3239505), Jun Itakura (554845), Shinya Sakita (3239508), Yasushi Ide (3239511), Masayuki Kurosaki (156560), Kouji Joko (3239496), Takashi Satou (3239469), Chikara Ogawa (3239478), Namiki Izumi (156627), Keiji Tsuji (3239502), Haruhiko Kobashi (3239490), Nobuyuki Enomoto (92837), Syotaro Tsuruta (3239475), Akeri Mitsuda (3239472), Yukio Osaki (170808), Kouichi Takaguchi (3239481), Hiroaki Okushin (3239499), Takashi Tamada (204139), Hiroyuki Hisai (3239493), Chitomi Hasebe (3239487), Hitoshi Yagisawa (147721), Yasuhiro Asahina (156563)   +22 more
core   +1 more source

Randomized clinical trial of nitazoxanide or sofosbuvir/daclatasvir for the prevention of SARS-CoV-2 infection [PDF]

, 2022
BACKGROUND: The COVER trial evaluated whether nitazoxanide or sofosbuvir/daclatasvir could lower the risk of SARS-CoV-2 infection. Nitazoxanide was selected given its favourable pharmacokinetics and in vitro antiviral effects against SARS-CoV-2 ...
Johnstone, Hilary, Hilary Johnstone, Joana Woods, Leah Ellis, Bosch, Bronwyn, Andrew Owen, Owen, Andrew, Carmen Perez Casas, Ellis, Leah, Woods, Joana, Hill, Andrew, Simiso Sokhela, Willem Daniel Francois Venter, Bronwyn Bosch, Akpomiemie, Godspower, Bryony Simmons, Godspower Akpomiemie, Andrew Hill, Casas, Carmen Perez, Sokhela, Simiso, Venter, Willem Daniel Francois, Simmons, Bryony   +21 more
core   +1 more source

Bemnifosbuvir: An HCV NS5B Inhibitor With Multiple Modes of Action

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 552-562, August 2026.
Bemnifosbuvir (BEM) is a potent, pan‐genotypic inhibitor targeting the hepatitis C virus (HCV) NS5B polymerase. Its antiviral activity was evaluated in an ascending dose phase I clinical trial involving 30 patients treated once a day for 7 days. After treatment initiation, plasma HCV RNA declined in a biphasic manner with a mean reduction of 2.3 log10 ...
Carolin Zitzmann, Ruy M. Ribeiro, Aurélien Marc, Xiao‐Jian Zhou, Alan S. Perelson   +4 more
wiley   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 510-519, August 2026.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, Volume 47, Issue 8, Page 696-712, August 2026.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source