Results 81 to 90 of about 8,174 (197)
Pakistan Armed Forces Medical Journal, 2020 Objective: To evaluate the efficacy of sofosbuvir with daclatasvir and its promising effects on liver functions especially in respect to earlier treatment failure patients to frame an appropriate regimen for them.
Sumetha Yaseen +5 more
doaj
Manipulation of both virus- and cell-specific factors is required for robust transient replication of a hepatitis C virus genotype 3a sub-genomic replicon [PDF]
, 2017 Hepatitis C virus (HCV) genotype (GT) 3 is the second most prevalent of the seven HCV genotypes and exhibits the greatest resistance to the highly potent, direct-acting antivirals (DAAs) that are currently in use. Previously a stable cell line harbouring
Badhan, A +4 more
core +1 more source
Liver International, Volume 45, Issue 8, August 2025.ABSTRACT Background and Aims In 2024, < 10% of hepatitis C virus (HCV) cases were treated in Eastern Europe and Central Asia (EECA) and the burden remains high. We aimed to estimate the cost‐effectiveness of treating anyone with HCV (‘treat all’) or targeting people who inject drugs (PWID) in 14 middle‐income EECA countries.
Josephine G. Walker +3 more
wiley +1 more source
Drugs in Context, 2020 Background: The once-daily oral combination of daclatasvir (DCV) and sofosbuvir (SOF), with or without ribavirin (RBV), is effective and well tolerated in patients with hepatitis C virus (HCV).
Rodolfo Sacco +26 more
doaj +1 more source
Current trends in the treatment of hepatitis C [PDF]
, 2016 Viral hepatitis, an inflammatory liver disease, is caused by various genotypes of hepatitis C viruses (HCV). Hepatitis C slowly sprouts into fibrosis, which progresses to cirrhosis.
Akhtar, Bushra +7 more
core +1 more source
Design Principles of Nanosensors for Multiplex Detection of Contaminants in Food
Small, Volume 21, Issue 26, July 3, 2025.This review discusses recent advancements in nanoparticle‐based nanosensors for multiplex detection of food contaminants, focusing on toxins and pathogens. It highlights the design principles, sensitivity, and selectivity of these sensors, offering insights into their practical applications for food safety monitoring and inspiring future innovations ...
Yang Zhang +10 more
wiley +1 more source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2015 The aim of review. To analyze antiviral activity of a new NS5A replication complex inhibitor daclatasvir in patients with chronic HCV-infection in relation to different genotypes, including patients with failure of previous antiviral therapy, with liver ...
M. V. Mayevskaya +2 more
doaj
Alimentary Pharmacology &Therapeutics, Volume 62, Issue 2, Page 146-158, July 2025.HCV clearance during direct‐acting antiviral therapy rapidly increases serum lipids and lipoproteins, potentially elevating cardiovascular risk. These metabolic changes, mediated by genes regulating hepatic lipogenesis, suggest that lipid levels should be closely monitored post‐SVR to assess long‐term cardiovascular implications.
Zahra Sarrafan‐Chaharsoughi +12 more
wiley +1 more source
Медицинский вестник Юга России, 2017 Objective: to give assessment of the effi cacy and safety of using asunaprevir in combination with daclatasvir in patients with chronic hepatitis C (HCV) with severe fi brosis and cirrhosis.
Elena B. Romanova +5 more
doaj +1 more source
An atom-efficient and convergent approach to the preparation of NS5A inhibitors by C-H activation [PDF]
, 2016 A novel approach of the convergent functionalisation of aryl dibromides to form NS5A type inhibitors using C–H activation is reported. The focus of investigation was to reduce the formation of homodimeric side product, as well as to investigate the scope
Moore, Thomas O. +2 more
core +1 more source