Results 61 to 70 of about 5,407 (151)

Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells

Journal of Experimental & Clinical Cancer Research, 2011
Background MDR1 gene encoding P-glycoprotein is an ATP-dependent drug efflux transporter and related to drug resistance of yolk sac carcinoma. Ultrasound microbubble-mediated delivery has been used as a novel and effective gene delivery method.
Wang Qiang, Wen Sheng, Liu Dongyao, Hua Yi, Bi Yang, He Yun, Li Mingyong, Zhu Jing, Lin Tao, He Dawei, Li Xuliang, Wang Zhigang, Wei Guanghui   +12 more
doaj   +1 more source

Dactinomycin [PDF]

Reactions Weekly, 2020
openaire   +2 more sources

Case report: Metastatic choriocarcinoma in the second trimester of a viable pregnancy with successful delivery and outcome after chemotherapy

Frontiers in Oncology
Metastatic choriocarcinoma during viable pregnancy is rare worldwide, and neonate survival following pregnancy termination in the second trimester is uncommon.
Yalin Tian, Yalin Tian, Jiayi Yu, Jiayi Yu, Xin Dan, Xin Dan, Tanglin Chen, Tanglin Chen, Yalin He, Yalin He   +9 more
doaj   +1 more source

Drug-induced sinusoidal obstruction syndrome: a real-world pharmacovigilance study based on the FDA Adverse Event Reporting System (FEARS)

BMC Pharmacology and Toxicology
Background Hepatic Sinusoidal Obstruction Syndrome (SOS) represents a rare but serious adverse drug reaction. This study aimed to identify the medications most frequently associated with SOS risk through the analysis of the United States Food and Drug ...
Cuicui Sun, Xiaoyan Yang, Lili Wang, Linlin Tang, Jinhua Chen   +4 more
doaj   +1 more source

Identification of Prognostic Biomarkers in Gene Expression Profile of Neuroblastoma Via Machine Learning

Pediatric Discovery
Neuroblastoma (NB) is a common pediatric solid malignancy characterized by heterogeneous clinical outcomes. The identification of predictive and interpretable prognostic biomarkers is critical for advancing precision medicine in NB.
Shuxin Tang, Jinhua Fan, Yupeng Cun
doaj   +1 more source

Urologic Cancer Drug Costs in Low- and Middle-Income Countries

Société Internationale d’Urologie Journal
All 189 World Bank member countries are classified by their capita gross national income into one of four income groups. In this review, we aim to explore the economic burden and management of urologic oncology conditions in low- and middle-income ...
Lan Anh S. Galloway, Brian D. Cortese, Ruchika Talwar   +2 more
doaj   +1 more source

Ex vivo discovery of synergistic drug combinations for hematologic malignancies

SLAS Discovery
Combination therapies have improved outcomes for patients with acute myeloid leukemia (AML). However, these patients still have poor overall survival.
Kamran A. Ali, Reecha D. Shah, Anukriti Dhar, Nina M. Myers, Cameron Nguyen, Arisa Paul, Jordan E. Mancuso, A. Scott Patterson, James P. Brody, Diane Heiser   +9 more
doaj   +1 more source

Advanced Wilms Tumor in a Middle‐Aged Adult: A Case Report

Clinical Case Reports
Wilms tumor, or nephroblastoma, is a malignant embryonal tumor originating from nephrogenic blastema, which imitates the histology of a developing kidney. Primarily, it occurs in children. Wilms tumor is exceedingly rare in adults, where the diagnosis is
Denis Mucunguzi, Bartholomeo Nicholaus Ngowi, Orgeness Jasper Mbwambo, Phinihas Jackson Mwijumbe, Nyamhanga Nsaho Maro, Abitalis Mayengela, Angumbwike Mwakitwange, Patrick Amsi, Donald Dominick Lema, Alex Mremi   +9 more
doaj   +1 more source

The role of glucocorticoids in hepatocellular carcinoma through integrated bioinformatics analysis and experimental validation

Scientific Reports
The most widespread primary liver cancer around the world is hepatocellular carcinoma (HCC), and its rising incidence and mortality rates are major challenges for public health.
Ao Wang, Xia Yin, Shijie Li, Yurou Fu, Tao Jiang, Jinfeng Fu   +5 more
doaj   +1 more source

A Novel Infection-Related Inflammatory Response-Related Genes Signature Predicts the Prognosis of Esophageal Squamous Cell Carcinoma

Clinical Medicine Insights: Oncology
Background: Our previous research showed that Porphyromonas gingivalis ( P. gingivalis ) infection can activate the inflammatory signaling pathway and promotes the malignancy development of esophageal squamous cell carcinoma (ESCC).
Jinyu Kong, Yiwen Liu, Jian Wang, Mengfan Qian, Wei Sun, Ling Xing   +5 more
doaj   +1 more source