Results 41 to 50 of about 5,407 (151)

A Critical Analysis of the Impact of Etoposide as a Topoisomerase II Inhibitor in Cervical Cancer Treatment: A Review

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian   +3 more
wiley   +1 more source

First-trimester abortion complicated with placenta accreta: A systematic review

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Placenta accreta is a potentially life-threatening condition that may complicate a first-trimester abortion in rare occasions, and it can be difficult to recognize.
Yeou-Lih Wang   +2 more
doaj   +1 more source

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review

open access: yesJournal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto   +6 more
wiley   +1 more source

Nasopharyngeal Rhabdomyosarcoma: A Rare Malignancy Incidentally Found in a Middle-Aged Male with a Diagnostic Dilemma

open access: yesEuropean Medical Journal Oncology, 2020
Nasopharyngeal rhabdomyosarcoma is a rare tumour of the paediatric age group that emerges from embryonal mesenchymal cells. Presented here is a case of a 54-year-old male of Asian ethnicity with a notable history of weight loss, lack of energy, anal ...
Muhammad Sohaib Asghar   +7 more
doaj  

Ewing Sarcoma

open access: yesClinical Pediatric Hematology-Oncology, 2019
Ewing sarcoma is the second most frequently occurring malignant tumor of the bone and soft tissue in adolescents and young adults. Genetically, Ewing sarcoma is characterized by balanced chromosomal translocation in which a member of FET gene family is ...
Hee Young Ju
doaj   +1 more source

Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1‐Related Tumor Predisposition Syndrome

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Anaplastic sarcoma of the kidney (ASK) is a DICER1‐associated malignant tumor presumed to arise in a benign precursor, pediatric cystic nephroma (PCN). However, the initial oncogenic alteration(s) associated with malignant transformation are unknown.
Nahir Cortes‐Santiago   +6 more
wiley   +1 more source

Dactinomycin-induced Hepatic Sinusoidal Obstruction Syndrome Responding to Treatment with N-acetylcysteine

open access: yesJournal of Cancer, 2011
Hepatic sinusoidal obstruction syndrome is commonly described in pediatric oncology as a complication of chemotherapy. It has also been occasionally reported in adult cancer patients. Treatment is largely supportive with fluid restriction. A 16-month-old
Anselm Chi-wai Lee, Peter Yu-tang Goh
doaj  

Duplex kidney complicated with preoperative inferior nephroblastoma rupture in children: a case report and literature review

open access: yesBMC Pediatrics, 2021
Background We admitted a child with a duplex kidney combined with preoperative rupture of nephroblastoma and used this case to discuss the clinical features and treatment of this disease. Case presentation We retrospectively analyzed the clinical data of
Yongxiang Zhao   +8 more
doaj   +1 more source

Sinonasal Sarcomas Management: An International Consensus Statement

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 1, Page 55-69, January 2026.
ABSTRACT Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.
Alessandro Vinciguerra   +51 more
wiley   +1 more source

Surgical resection of a massive residual retroperitoneal mass after chemotherapy for a paratesticular rhabdomyosarcoma: a case report

open access: yesJournal of Medical Case Reports, 2022
Introduction Paratesticular rhabdomyosarcoma is a rare and aggressive mesenchymal tumor, accounting for only 7% of all rhabdomyosarcomas. It is mainly encountered in children and adolescents.
Takoua Chalouati   +7 more
doaj   +1 more source

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