Results 91 to 100 of about 57,080 (289)
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract Post‐harvest agricultural residues in Latin America are commonly underutilized, leading to greenhouse gas emissions and lost opportunities for bio‐based value creation. This study tests the hypothesis that decentralized, farmer‐scale pyrolysis technologies can deliver comparable agronomic benefits while exhibiting distinct techno‐economic and ...
Juan F. Saldarriaga +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley +1 more source
Insulin/IGF‐1‐mediated longevity is marked by reduced protein metabolism
Molecular Systems Biology, 2013 Mutations in the daf‐2 gene of the conserved Insulin/Insulin‐like Growth Factor (IGF‐1) pathway double the lifespan of the nematode Caenorhabditis elegans. This phenotype is completely suppressed by deletion of Forkhead transcription factor daf‐16.
Gerdine J Stout +10 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad +4 more
wiley +1 more source
BMEMat, EarlyView.The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng +10 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi +6 more
wiley +1 more source
Cation Distribution in Li2CaSiO4:Gd, Pr, Na Uncovered Through Anomalous Diffraction
European Journal of Inorganic Chemistry, EarlyView.Li2CaSiO4 co‐doped with Gd3+ and Pr3+ shows strong blue‐to‐UV‐B up‐conversion. Herein, we explore the doping element distribution in order to discern the reason for the strongly supportive co‐doping effect using high‐resolution Rietveld refinement and multiple‐edge anomalous dispersion measurements.
Christoph Rick +4 more
wiley +1 more source
BuildingsTo study how varying the parameters of expansion joints and bearing supports (E-B parameters) affects the dynamic response of a coupled vehicle–bridge system for curved girder bridges, a dynamic response analysis method for the coupled vehicle–joint ...
Yu Zheng +9 more
doaj +1 more source
C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress.
PLoS Genetics, 2012 FoxO transcription factors and sirtuin family deacetylases regulate diverse biological processes, including stress responses and longevity. Here we show that the Caenorhabditis elegans sirtuin SIR-2.4--homolog of mammalian SIRT6 and SIRT7 proteins ...
Wei-Chung Chiang +9 more
doaj +1 more source
, 2022 (A) Bar graph of the percent animals with DAF-16a::GFP (zIs356) positive vesicles in the intestinal cells at larval stages L1-L4 and young adults of wild-type and tbc-2(tm2241) animals at 20°C.
Thomas Liontis (13184383) +7 more
core +1 more source