Daidzein: A review of pharmacological effects
African Journal of Traditional, Complementary and Alternative Medicines, 2016 Background: Daidzein is an isoflavone with extensive nutritious value and is mainly extracted from soy plants. It is also called phytoestrogen due to its structural similarity to the human hormone estrogen. However, daidzein is distinct from estrogen due to the specificity of the estrogen receptor (ER) complex.
Sun, M-Y +5 more
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Influence of Daidzein and Daidzein Metabolites on Lifespan and Stress Resistance in Caenorhabditis Elegans [PDF]
Proceedings of the 2016 International Conference on Biomedical and Biological Engineering, 2016 C aenorhabditis elegans (C. elegans) was used as an animal model to study the influence of isoflavone daidzein and daidzein metabolites, including dihydrodaidzein (DHD), O-desmethylangolensin (O-Dma) and equol, on lifespan in C. elegans at the concentration of 0.1 mmol/L. The results showed that equol significantly increased the lifespan of C. elegans;
Xiuling Wang +3 more
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A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]
, 2017 There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C. +11 more
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Italian Journal of Animal Science, 2018 An experiment was conducted to determine the effects of soy isoflavone daidzein on ruminal fermentation, microbial protein synthesis and rumen bacterial community in beef cattle.
Xiang H. Zhao +8 more
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Lactulose increases equol production and improves liver antioxidant status in barrows treated with Daidzein. [PDF]
PLoS ONE, 2014 Equol, one of the intestinal microflora metabolites of daidzein, has gained much attention for having greater bioactivity than its precursor (daidzein and daidzin) and seeming to be promoted by hydrogen gas.
Weijiang Zheng, Yanjun Hou, Wen Yao
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Theoretical study on the glycosidic C–C bond cleavage of 3’’-oxo-puerarin
Scientific Reports, 2023 Puerarin, daidzein C-glucoside, was known to be biotransformed to daidzein by human intestinal bacteria, which is eventually converted to (S)-equol. The metabolic pathway of puerarin to daidzein by DgpABC of Dorea sp. PUE strain was reported as puerarin (
Jongkeun Choi +3 more
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Chemotactic response of the flavonoid daidzein and its effect on the composition of the rumen bacterial community [PDF]
, 2014 Daidzein is one of common metabolites in plants and has chemotactic effect on soil bacteria that colonize the plants. There are several tests to assess bacterial chemotaxis, but none focused on rumen bacteria. Therefore, the aim of this study was to test
Galicia Jiménez, Mónica M. +4 more
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Neural Regeneration Research, 2017 3′-Daidzein sulfonate sodium is a new synthetic water-soluble compound derived from daidzein (an active ingredient of the kudzu vine root). It has been shown to have a protective effect on cerebral ischemia/reperfusion injury in rats.
Wa Yuan +6 more
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Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia
Foods, 2021 The intake of isoflavones is presumed to be associated with health benefits in humans, but also potential adverse effects of isoflavones are controversially discussed.
Sebastian Tobias Soukup +5 more
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Preliminary investigation of the influence of long-term dietary isoflavone intake on reproductive tract histology and sex steroid receptor expression in female domestic cats (Felis catus) [PDF]
, 2012 Genistein and daidzein are isoflavones which are reported to influence the reproductive system in a variety of mammalian species. This pilot study aimed to determine if dietary isoflavones could potentially influence reproductive tract histology or ...
Cave, NJ +4 more
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