Results 21 to 30 of about 13,585 (158)

Drug like potential of Daidzein using SwissADME prediction: In silico Approaches

open access: yesPHYTONutrients, 2023
In the early stages of drug development, predicting the drug candidates' absorption, distribution, metabolism, and elimination (ADME) profiles prior to their synthesis may help in the selection of potential candidates.
Haseeba Sardar
semanticscholar   +1 more source

Comparison of the effect of quercetin and daidzein on production performance, anti-oxidation, hormones, and cecal microflora in laying hens during the late laying period

open access: yesPoultry Science, 2023
This study aims to compare the effect of quercetin and daidzein on production performance, anti-oxidation, hormones, and cecal microflora in laying hens during the late laying period.
Jiayan Liu   +8 more
semanticscholar   +1 more source

Therapeutic Potential of Isoflavones with an Emphasis on Daidzein

open access: yesOxidative Medicine and Cellular Longevity, 2021
Daidzein is a phytoestrogen isoflavone found in soybeans and other legumes. The chemical composition of daidzein is analogous to mammalian estrogens, and it could be useful with a dual-directional purpose by substituting/hindering with estrogen and ...
Mohammed M. Alshehri   +16 more
semanticscholar   +1 more source

Daidzein Inhibits Human Platelet Activation by Downregulating Thromboxane A2 Production and Granule Release, Regardless of COX-1 Activity

open access: yesInternational Journal of Molecular Sciences, 2023
Platelets play crucial roles in cardiovascular diseases (CVDs) by regulating hemostasis and blood coagulation at sites of blood vessel damage. Accumulating evidence indicates daidzein inhibits platelet activation, but the mechanism involved has not been ...
Hyun-Jin Hong, G. Nam, K. Nam
semanticscholar   +1 more source

Isoflavones daidzin and daidzein inhibit lipopolysaccharide-induced inflammation in RAW264.7 macrophages

open access: yesChinese Medicine, 2022
Background Inflammation contributes to various diseases and soybeans and legumes are shown to reduce inflammation. However, the bioactive ingredients involved and mechanisms are not completely known.
Yi Tan, Xutao Zhang, San-Che-Ang Wai
semanticscholar   +1 more source

Effects of soy isoflavonoids (genistein and daidzein) on endometrial receptivity [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): This study aimed to examine the effects of genistein and daidzein on endometrial receptivity by histopathological, immunohistochemical, and biochemical techniques.Materials and Methods: In this study, 72 female Sprague-Dawley rats were ...
Erdem Toktay   +6 more
doaj   +1 more source

Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways

open access: yesMolecules, 2022
The intestinal epithelium provides an important barrier against bacterial endotoxin translocation, which can regulate the absorption of water and ions. The disruption of epithelial barrier function can result in water transport and tight junction damage,
Bao-Ping Zhang   +5 more
semanticscholar   +1 more source

The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures. [PDF]

open access: yesPLoS ONE, 2016
Obesity-induced inflammation caused by adipocyte-macrophage interactions plays a critical role in developing insulin resistance, and peroxisome proliferator-activated receptors (PPARs) regulate inflammatory gene expression in these cells.
Yuri Sakamoto   +5 more
doaj   +1 more source

Biotransformation of Daidzein to Diadzein-7-Glucoside and Its Anti-allergic Activity

open access: yesNatural Product Communications, 2017
The biotransformation of daidzein and its diacetate was investigated using cultured plant cells of Phytolacca americana as biocatalysts. Daidzein was glucosylated to the corresponding 7- O -β-D-glucoside.
Yuya Fujitaka   +6 more
doaj   +1 more source

Synergistic antimicrobial activities of epigallocatechin gallate, myricetin, daidzein, gallic acid, epicatechin, 3‐hydroxy‐6‐methoxyflavone and genistein combined with antibiotics against ESKAPE pathogens

open access: yesJournal of Applied Microbiology, 2021
To verify synergistic effects, we investigated the antimicrobial activity of seven phenolic phytochemicals (gallic acid; epicatechin; epigallocatechin gallate; daidzein; genistein; myricetin; 3‐hydroxy‐6‐methoxyflavone) in combination with six ...
D. Buchmann   +5 more
semanticscholar   +1 more source

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