Advanced Science, EarlyView.The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan +16 more
wiley +1 more source
A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
Advanced Science, EarlyView.An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su +10 more
wiley +1 more source
An investigation into the effects of different housing and feeding systems on behaviour and milk production of dairy ewes in mid and late stages of lactation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Animal Science at Massey University, Manawatu, New Zealand [PDF]
, 2018 The following have been removed for copyright reasons, but may be accessed via their source listed in the references: Figures 1.1 p. 9 (=Fig 2, p. 2715), 1.2 p. 10 (=Fig A p. 86), 1.3 p. 15 (=Fig 2 p. 261), 1.4 p. 16 (=Fig 2 BCS p. 36), 1.6 p.
Bliss, April Elizabeth
core
Advanced Science, EarlyView.TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source
Prediction of random-regression coefficient for daily milk yield after 305 days in milk by using the regression-coefficient estimates from the first 305 days. [PDF]
Asian-Australas J Anim Sci, 2018 Yamazaki T +4 more
europepmc +1 more source
Labour efficiency on-farm [PDF]
, 2007 End of project reportImprovements in milking efficiency have a greater influence than any other aspect of the dairy farmers work on overall farm labour inputs (Whipp, 1992).
Boyle, Laura +7 more
core
Advanced Science, EarlyView.Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao +16 more
wiley +1 more source
The protection of the unsaturated fatty acids of dried grass and sunflower seed against biohydrogenation by rumen micro-organisms : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University [PDF]
, 1974 Ryegrass which had been dried and treated with HCHO was incubated with the rumen contents of a pasture-grazed cow. The protein in the grass was protected from degradation by the rumen microbes.
Smeaton, Duncan Colquhoun
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Advanced Science, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source
The effect of breeding area, stage of lactation and herd on milk yield traits of Pag sheep
Mljekarstvo, 2012 The objective of this study was to determine the effect of different breeding areas (south-west and north-east part of the island of Pag) on daily milk, fat and protein yield in Pag sheep. The aim of thisstudy was also to determine the shape of lactation
Zdravko Barać +2 more
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