Results 41 to 50 of about 881,906 (297)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Urbanisation and everyday mobility.Long-term changes of travel in urban areas of Sweden
Cybergeo, 2005 This paper examines the long-term changes of travel patterns in urbanized and semi-urbanized areas of Sweden. Travel survey data reveal a connection between built-up area size/density and distance travelled. This relation is not linear.
Bertil Vilhelmson
doaj +1 more source
Biomechanics of Pediatric Manual Wheelchair Mobility [PDF]
, 2015 Currently, there is limited research of the biomechanics of pediatric manual wheelchair mobility. Specifically, the biomechanics of functional tasks and their relationship to joint pain and health is not well understood.
Aurit, Christine M. +5 more
core +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
All Limbs Lead to the Trunk [PDF]
, 2017 This poster describes the development of and the psychometric properties of the trunk scale that measures the voluntary motor ability in the thoracic and upper lumbar regions.
Atkinson, PhD, PT, Darryn +1 more
core +1 more source
Exact solution of gyration radius of individual's trajectory for a simplified human mobility model
, 2010 Gyration radius of individual's trajectory plays a key role in quantifying human mobility patterns. Of particular interests, empirical analyses suggest that the growth of gyration radius is slow versus time except the very early stage and may eventually ...
Bazzani A +8 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
“We can all just get on a bus and go” : Rethinking independent mobility in the context of the universal provision of free bus travel to young Londoners [PDF]
, 2013 This paper uses qualitative data from interviews with 118 young Londoners (age 12-18) to examine how the universal provision of free bus travel has affected young people’s independent mobility. Drawing on Sen’s ‘capabilities approach’, we argue that free
Alasdair Jones +21 more
core +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Movilidad cotidiana en tiempos de Covid-19: un análisis desde los arreglos intrafamiliares en Bogotá
Bulletin de l'Institut Français d'Études Andines, 2022 This article analyzes mobility strategies implemented by the households of Bogota in response to the Covid-19 crisis. Based on thirty-six family chronicles developed by a group of university students from Bogota, this study examines the relationship ...
Hernando Sáenz-Acosta +2 more
doaj +1 more source