Results 41 to 50 of about 232,639 (262)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan +15 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cybergeo, 2023 In Cameroon, trips undertaken by women are generally confined to a small area around their home and are closely monitored by men. In this context, we examine how the appropriation, adaptation, and use of mobile phones by women can help them gain more ...
Jérémy Pasini
doaj +1 more source
Tracking the Temporal Flows of Mobile Communication in Daily Life
New Media & Society, 2022 Prior theoretical perspectives assert that mobile media and communication accelerate time perception. To test this hypothesis, we coupled mobile app logs and experience sampling to capture social app use and time perception in daily life. Participants (N = 132) provided self-reports of time perception (n = 9,081) and recordings of social app use (n = 2,
Morgan Quinn Ross +4 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Analyser politique et savoir en action. Éclairages à partir du cas de la couverture de l’A6b
Métropoles, 2018 This paper tackles the issue of the relation between norm and action in the field of urbanism, by using a pragmatic analysis of local policies. Norm here means a rule that actors are supposed to comply with, whether because it is prescriptive or because ...
Caroline Gallez
doaj +1 more source
A Probabilistic Approach for Discovering Daily Human Mobility Patterns with Mobile Data [PDF]
, 2020 Discovering human mobility patterns with geo-location data collected from smartphone users has been a hot research topic in recent years. In this paper, we attempt to discover daily mobile patterns based on GPS data. We view this problem from a probabilistic perspective in order to explore more information from the original GPS data compared to other ...
Weizhu Qian +2 more
openaire +2 more sources