Results 61 to 70 of about 122,160 (314)

Regional climate projections in two alpine river basins: Upper Danube and Upper Brahmaputra [PDF]

, 2011
Projections from coarse-grid global circulation models are not suitable for regional estimates of water balance or trends of extreme precipitation and temperature, especially not in complex terrain.
Yaoming, Ma, Dobler, Andreas, A. Dobler, M. Yaoming, Ahrens, Bodo, Kienberger, Stefan, S. Kienberger, B. Ahrens, N. Sharma, Sharma, Nayan   +9 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Trends and variability in daily precipitation in Scotland [PDF]

Procedia Environmental Sciences, 2011
The objective of this research is to analyse temporal changes in historic rainfall variability across Scotland using different measures of variability. The CUSUM and sequential Mann-Kendall test applied to records from 28 weather stations with up to 80 years of daily precipitation data reveal the occurrence of abrupt changes in the rainfall trends ...
Afzal, M, Mansell, MG, Gagnon, AS
openaire   +1 more source

Estimation of missing precipitation records using modular artificial neural networks

, 2012
Estimation of missing precipitation records is one of the important tasks in hydrological study. The completeness of precipitation data leads to more accurate results from the hydrological models.
Wong, K.W., Fung, C.C., Chun Che Fung, Kok Wai Wong, Kajornrit, J., Jesada Kajornrit   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Runoff modelling in glacierized Central Asian catchments for present-day and future climate [PDF]

, 2006
A conceptual precipitation–runoff model was applied in five glacierized catchments in Central Asia. The model, which was first developed and applied in the Alps, works on a daily time step and yields good results in the more continental climate of the ...
Braun, L. N., Becht, M., Weber, M., Hagg, Wilfried   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Daily precipitation concentration across Europe 1971–2010 [PDF]

Natural Hazards and Earth System Sciences, 2012
Daily Precipitation Concentration Index (CI) was used in this paper to investigate the statistical structure of daily precipitation across Europe based on 530 daily rainfall series for the period 1971–2010.
N. Cortesi, J. C. Gonzalez-Hidalgo, M. Brunetti, J. Martin-Vide   +3 more
doaj   +1 more source

Simulation and Evaluation of Statistical Downscaling of Regional Daily Precipitation over North China Based on Self-Organizing Maps

Atmosphere, 2022
A statistical downscaling method based on Self-Organizing Maps (SOM), of which the SOM Precipitation Statistical Downscaling Method (SOM-SD) is named, has received increasing attention.
Yongdi Wang, Xinyu Sun
doaj   +1 more source

On the Internal Variability of Simulated Daily Precipitation* [PDF]

Journal of Climate, 2015
AbstractClimate model simulations are currently the main tool to provide information about possible future climates. Apart from scenario uncertainties and model error, internal variability is a major source of uncertainty, complicating predictions of future changes.
Jürg Luterbacher, Elena Xoplaki, Sophie Fukutome, Silvio Gualdi, Enrico Scoccimarro, Matteo Zampieri, Andrea Toreti, Anne Schindler   +7 more
openaire   +1 more source