Results 71 to 80 of about 431,478 (301)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Multi-satellite observed responses of precipitation and its extremes to interannual climate variability [PDF]

, 2011
The consistency of precipitation variability estimated from the multiple satellite-based observing systems is assessed. There is generally good agreement between TRMM TMI, SSM/I, GPCP and AMSRE datasets for the inter-annual variability of precipitation ...
Adler, Adler, Allan, Allan, Andersson, Andrews, Arkin, Bengtsson, Chou, Chunlei Liu, Dee, Emori, Field, Gastineau, Gu, Haerter, Held, Huffman, Huffman, John, Lambert, Lau, Lenderink, Liepert, Lobl, Maidment, Meehl, Min, Ming, Mitchell, Muller, O'Gorman, Pall, Quartly, Richard P. Allan, Sohn, Stephens, Sugiyama, Trenberth, Trenberth, Vila, Wang, Wentz, Wentz, Wilcox, Zahn, Zhang, Zhou   +47 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Generation of Stochastic Daily Precipitation for China Based on Empirical Orthogonal Function Analysis

Redai dili
Historical precipitation data are crucial for assessing the risks associated with natural disasters such as droughts and floods. However, some extreme precipitation scenarios may not have been included in historical records, particularly in China where ...
Yang Yifei, Fang Weihua, Zheng Jinli, Fu Jingxuan   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Precipitation Protocols [PDF]

, 2003
The purpose of this activity is to determine the amount of moisture input to the local environment by measuring rain and snowfall and to measure the pH of precipitation.
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core  

Wetland restoration design modifications to mitigate climate change impacts at Delaware Water Gap National Recreation Area: A case study report [PDF]

, 2020
Historic temperature and precipitation trends, and their projected climate change effects, were used to inform the development of wetland design tactics to restore a 30-acre degraded wetland at Delaware Water Gap National Recreation Area.
Noon, Kevin F.
core  

Local impact analysis of climate change on precipitation extremes : are high-resolution climate models needed for realistic simulations? [PDF]

, 2016
This study explores whether climate models with higher spatial resolutions provide higher accuracy for precipitation simulations and/or different climate change signals.
Brisson, Erwan, De Troch, Rozemien, Giot, Olivier, Hamdi, Rafiq, Saeed, Sajjad, Tabari, Hossein, Termonia, Piet, Van Lipzig, Nicole, Willems, Patrick   +8 more
core   +3 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Evaluation of ERA-Interim reanalysis precipitation products using England and Wales observations [PDF]

, 2015
Precipitation forecast data from the ERA-Interim reanalysis (33 years) are evaluated using the daily England and Wales Precipitation (EWP) observations obtained from a rain gauge network.
Blackburn, M., de Leeuw, J., Methven, J.
core   +1 more source