Results 71 to 80 of about 773,400 (308)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Modelling surface climate over complex terrain for landscape ecology [PDF]
, 2000 Climate exerts a fundamental control on ecosystem function, species diversity and distribution. Topographic variability may influence surface climate, through processes operating at a landscape- scale.
Joyce, Andrew Noel, Joyce, A.N.
core
The association of cold weather and all-cause and cause-specific mortality in the island of Ireland between 1984 and 2007 [PDF]
, 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
McAvoy, H +7 more
core +1 more source
STEAD: a high-resolution daily gridded temperature dataset for Spain [PDF]
Earth System Science Data, 2019 Using 5520 observatories covering the whole territory of Spain (about 1 station per 90 km2 considering the whole period), a daily gridded maximum and minimum temperature was built covering a period from 1901 to 2014 in peninsular Spain and 1971 to
R. Serrano-Notivoli +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Influence of Atmospheric Rivers on Alaskan River Ice
Geophysical Research LettersAtmospheric rivers (ARs) transport vast amounts of moisture from low to high latitude regions. One region particularly impacted by ARs is Interior Alaska (AK). We analyze the impact of ARs on the annual river ice breakup date for 26 locations in AK.
Russ Limber +4 more
doaj +1 more source
Long-term predictability of mean daily temperature data [PDF]
Nonlinear Processes in Geophysics, 2005 We quantify the long-term predictability of global mean daily temperature data by means of the Rényi entropy of second order K2. We are interested in the yearly amplitude fluctuations of the temperature. Hence, the data are low-pass filtered.
W. von Bloh, M. C. Romano
doaj
Long-term trends in daily temperature extremes over Mongolia
Weather and Climate Extremes, 2015 Various indices have been used to investigate recent changes in the annual frequencies of extreme temperature events in Mongolia. A high-quality daily temperature dataset including 53 station records was used to determine trends from 1961 to 2010.
Dulamsuren Dashkhuu +3 more
doaj +1 more source
Scientific Data, 2023 Knowledge about local air temperature variations and extremes in Antarctica is of large interest to many polar disciplines such as climatology, glaciology, hydrology, and ecology and it is a key variable to understand climate change.
Eva Bendix Nielsen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source