Results 41 to 50 of about 6,683,927 (310)

Formation of an Explosively Formed Penetrator Warhead Using a Step-Shaped Charge

Shock and Vibration, 2022
In this study, the formation mechanism of an explosively formed penetrator (EFP) with tail fins was analyzed. Through static denotation and dynamic flight tests, the feasibility of using a step-shaped liner during the formation of an EFP with tail fins ...
Weizhan Wang, Zhigang Chen, Baoliang Yang, Tong Jing, Fangao Meng, Taiyong Zhao   +5 more
doaj   +1 more source

Lysine Crotonylation: An Emerging Player in DNA Damage Response

Biomolecules, 2022
The DNA damage response (DDR) system plays an important role in maintaining genome stability and preventing related diseases. The DDR network comprises many proteins and posttranslational modifications (PTMs) to proteins, which work in a coordinated ...
Yuqin Zhao, Shuailin Hao, Wenchi Wu, Youhang Li, Kaiping Hou, Yu Liu, Wei Cui, Xingzhi Xu, Hailong Wang   +8 more
doaj   +1 more source

New methodology for calculating damage variables evolution in Plastic Damage Model for RC structures [PDF]

, 2017
The behavior of reinforced concrete (RC) structures under severe demands, as strong ground motions, is highly complex; this is mainly due to joint operation of concrete and steel, with several coupled failure modes.
Alfarah, Bashar, López Almansa, Francisco, Oller Martínez, Sergio Horacio   +2 more
core   +2 more sources

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

EMBO Reports
Cyclosporin A (CsA) induces DNA double-strand breaks in LIG4 syndrome fibroblasts, specifically upon transit through S-phase. The basis underlying this has not been described.
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll   +5 more
doaj   +1 more source

Exercise Reduce Oxidative Damage in Pregnancy [PDF]

, 2011
Pregnancy is a vulnerable condition to all kinds of "stress", resulting in changes of physiological and metabolic functions. This research aims to determine effect of exercise during pregnancy in reducing oxidative demage marked by decrease of ...
Bagiada, A. (A), Pangkahila, A. (A), Surya, I. G. (I), Wagey, F. W. (F)   +3 more
core  

Interplay of space radiation and microgravity in DNA damage and DNA damage response [PDF]

, 2017
In space, multiple unique environmental factors, particularly microgravity and space radiation, pose constant threat to the DNA integrity of living organisms.
Lu, Tao, Moreno-Villanueva, María, Wong, Michael, Wu, Honglu, Zhang, Ye   +4 more
core   +2 more sources

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy

Cell Reports, 2014
BAF180, a subunit of the PBAF chromatin remodeling complex, is frequently mutated in cancer. Although PBAF regulates transcription, it remains unclear whether this is what drives tumorigenesis in cells lacking BAF180.
Peter M. Brownlee, Anna L. Chambers, Ross Cloney, Alessandro Bianchi, Jessica A. Downs   +4 more
doaj   +1 more source

Damage classification in reinforced concrete beam by acoustic emission signal analysis [PDF]

, 2013
Acoustic Emission (AE) is a non-destructive testing technique which can be used to identify both the damage level and the nature of that damage such as tensile cracks and shear movements at critical zones within a structure.
Aggelis, Aggelis, Aggelis, Carpinteri, Colombo, CU, Degala, Golaski, Holford, Holford, Karen M. Holford, Kocur, Lakshmi, Nair, Norazura Muhamad Bunnori, Ohtsu, Ohtsu, Ohtsu, Proverbio, Rhys Pulin, Shahidan, Shahiron Shahidan, Shiotani, Soulioti, Yuyama   +24 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source