Results 21 to 30 of about 6,683,927 (310)

Coupled thermo-mechanical damage modelling for structural steel in fire conditions [PDF]

open access: yes, 2020
This paper aims at developing a coupled thermo-mechanical damage model for structural 6 steel at elevated temperatures. The need for adequate modelling of steel deterioration behaviour 7 remains a challenging task in structural fire engineering because ...
Ayoub, A., D'Mello, C., Lu, W.
core   +1 more source

A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

open access: yesNature Communications, 2019
Topoisomerase 2 (Top2) is known to resolve DNA topological stress through double strand breaks (DSBs), yet Top2 inhibition has been reported to result in a significant amount of single-strand breaks (SSBs).
William H. Gittens   +5 more
doaj   +1 more source

Damage monitoring in sandwich beams by modal parameter shifts: a comparative study of burst random and sine dwell vibration testing [PDF]

open access: yes, 2010
This paper presents an experimental study on the effects of multi-site damage on the vibration response of honeycomb sandwich beams, damaged by two different ways i.e., impact damage and core-only damage simulating damage due to bird or stone impact or ...
Gourinat, Yves   +2 more
core   +3 more sources

ALVEOLAR DAMAGE: EPITHELIAL DAMAGE AND ENDOTHELIAL DAMAGE

open access: yesJournal of Toxicologic Pathology, 1989
The alveolar damage produced by a variety of toxic agents, whether air-borne or blood-borne, progresses to a sequence of nonspecific changes histologically regarded as diffuse alveolar damage. Ultrastructurally, their alveolar damage can be divided into epithelial and endothelial type according to their target cells. The epithelial and endothelial type
Takesaburo Ogata   +4 more
openaire   +2 more sources

PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling

open access: yesNature Communications, 2019
The kinase PLK1 has important roles during cell division, including mitotic entry and bipolar spindle formation. Here, the authors show that PLK1 also functions in centromere protection, with loss leading to DNA unwinding by Bloom’s syndrome helicase and
Owen Addis Jones   +4 more
doaj   +1 more source

Real time structural damage assessment from vibration measurements [PDF]

open access: yes, 2011
Damage identification in civil engineering structures using vibration measurements has become an important area of research. A reliable and cost effective method is required to detect and quantify local damage in the structures. The objective of this new
Alani, A.M., Chen, H.-P., Maung, T.S.
core   +1 more source

Bone Marrow CD133 Stem Cells Ameliorate Visual Dysfunction in Streptozotocin-induced Diabetic Mice with Early Diabetic Retinopathy

open access: yesCell Transplantation, 2018
Diabetic retinopathy (DR), one of the leading causes of vision loss worldwide, is characterized by neurovascular disorders. Emerging evidence has demonstrated retinal neurodegeneration in the early pathogenesis of DR, and no treatment has been developed ...
Liyuan Rong   +9 more
doaj   +1 more source

Automation of the cytokinesis-block micronucleus cytome assay by laser scanning cytometry and its potential application in radiation biodosimetry

open access: yesBioTechniques, 2014
Here we describe the adaptation of laser scanning cytometry (LSC) to measure micronuclei (MN) automatically in lymphocytes. MN frequencies were determined in irradiated human lymphocytes using the cytokinesis-block technique, and the results from LSC ...
Maxime François   +3 more
doaj   +1 more source

A new mechanical structural damage feature index based on HHT [PDF]

open access: yes, 2018
A new damage feature index is presented for the structural health monitoring based on Hilbert-Huang transform (HHT). The energy marginal spectrum of the dynamic signal is used to construct damage characteristic parameter, which can reflect the signal ...
Hua, Lin, Wang, Fusheng, Yue, Zhufeng
core   +3 more sources

Damage limitation

open access: yeseLife, 2016
A spring-loaded mechanism can explain the activation process for a protein that has a crucial role in maintaining the genomic integrity of immature eggs ...
Ivano Amelio, Gerry Melino
openaire   +3 more sources

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