Results 21 to 30 of about 3,622,932 (286)
Measurements of elastic properties and their dependencies within a damage mechanics workflow
Experimental rock mechanics testing provides a controlled and effective method for measuring physical properties, their dependencies, and their evolution due to the addition of localized microcracks.
Erik P. Knippel +3 more
doaj +1 more source
The Damage in Negotiating Damages
Abstract This chapter advances a new analysis of One Step negotiating damages, urging that the claim underpinning these awards is a claim for restitution for unjust enrichment, not a claim for damages in contract. Moreover, this unjust enrichment claim is for the enrichment derived by D from its use of C’s property without C’s consent ...
openaire +3 more sources
Cyclosporin A (CsA) induces DNA double-strand breaks in LIG4 syndrome fibroblasts, specifically upon transit through S-phase. The basis underlying this has not been described.
Marisa Bedir +5 more
doaj +1 more source
Lysine Crotonylation: An Emerging Player in DNA Damage Response
The DNA damage response (DDR) system plays an important role in maintaining genome stability and preventing related diseases. The DDR network comprises many proteins and posttranslational modifications (PTMs) to proteins, which work in a coordinated ...
Yuqin Zhao +8 more
doaj +1 more source
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Formation of an Explosively Formed Penetrator Warhead Using a Step-Shaped Charge
In this study, the formation mechanism of an explosively formed penetrator (EFP) with tail fins was analyzed. Through static denotation and dynamic flight tests, the feasibility of using a step-shaped liner during the formation of an EFP with tail fins ...
Weizhan Wang +5 more
doaj +1 more source
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian +13 more
wiley +1 more source
BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy
BAF180, a subunit of the PBAF chromatin remodeling complex, is frequently mutated in cancer. Although PBAF regulates transcription, it remains unclear whether this is what drives tumorigenesis in cells lacking BAF180.
Peter M. Brownlee +4 more
doaj +1 more source
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi +10 more
wiley +1 more source
TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription
DNA double-strand breaks (DSBs) induced by topoisomerase II (TOP2) are rejoined by TDP2-dependent non-homologous end-joining (NHEJ) but whether this promotes or suppresses translocations is not clear. Here the authors show that TDP2 suppresses chromosome
Fernando Gómez-Herreros +6 more
doaj +1 more source

