Results 31 to 40 of about 6,683,927 (310)

The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins

open access: yesNature Communications, 2016
Werner syndrome is a progeroid disease characterised by genetic instability due to mutations to the WRN helicase/exonuclease. Here the authors define a novel Ku binding motif (KBM) and show that two such motifs facilitate the involvement of WRN in DNA ...
Gabrielle J. Grundy   +7 more
doaj   +1 more source

An investigation on vibration-based damage detection in circular plates [PDF]

open access: yes, 2009
This study aims at the development of vibration-based health monitoring (VHM) methodology for thin circular plates. The possibility of using the first several natural frequencies of a circular plate for damage detection purposes is investigated first ...
D.G. Gorman   +5 more
core   +1 more source

Basic concepts and models in continuum damage mechanics [PDF]

open access: yes, 2007
In this paper, we present some basic elements of macroscopic modelling of damage. We then recall the general approach of continuum damage based on the thermodynamics of irreversible processes and its application to isotropic damage modelling.
Cormery, Fabrice   +2 more
core   +3 more sources

Kuchmagate's Collateral Damage [PDF]

open access: yes, 2001
Dubois Patrick. VINOT (Joseph). In: , . Le dictionnaire de pédagogie et d'instruction primaire de Ferdinand Buisson : répertoire biographique des auteurs. Paris : Institut national de recherche pédagogique, 2002. p. 139.
Lynch, Tammy
core   +2 more sources

Olfactory Ensheathing Cells Inhibit Gliosis in Retinal Degeneration by Downregulation of the Müller Cell Notch Signaling Pathway

open access: yesCell Transplantation, 2017
Retinal regeneration and self-repair, whether in response to injury or degenerative disease, are severely impeded by glial scar formation by Müller cells (specialized retinal macroglia). We have previously demonstrated that the activation of Müller cells
Jing Xie   +5 more
doaj   +1 more source

Liver stiffness and arterial stiffness/abnormal central hemodynamics in the early stage of heart failure

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2018
Background: It remains to be clarified whether liver stiffness is a direct risk factor for heart failure (HF) or whether its association with HF is mediated by vascular damage.
Yoichi Iwasaki   +8 more
doaj   +1 more source

Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells

open access: yesScientific Reports, 2021
In response to UV irradiation, translesion DNA synthesis (TLS) utilizes specialized DNA polymerases to bypass replication-blocking lesions. In a well-established polymerase switch model, Polη is thought to be a preferred TLS polymerase to insert correct ...
Tonghui Bi   +3 more
doaj   +1 more source

Measurements of elastic properties and their dependencies within a damage mechanics workflow

open access: yesRock Mechanics Bulletin, 2023
Experimental rock mechanics testing provides a controlled and effective method for measuring physical properties, their dependencies, and their evolution due to the addition of localized microcracks.
Erik P. Knippel   +3 more
doaj   +1 more source

Experimental methodology of study of damage initiation and development in textile composites in uniaxial tensile test [PDF]

open access: yes, 2008
Damage in textile composites is closely connected with the internal micro- and meso-geometry of the reinforcement, and reveals features, which are not present in the damage processes in classical laminates. This paper proposes a test sequence intended to
Baudry, F.   +6 more
core   +2 more sources

Patterns and correlates of claims for brown bear damage on a continental scale [PDF]

open access: yes, 2017
Wildlife damage to human property threatens human-wildlife coexistence. Conflicts arising from wildlife damage in intensively managed landscapes often undermine conservation efforts, making damage mitigation and compensation of special concern for ...
Agnieszka, Olszańska   +22 more
core   +1 more source

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