Results 91 to 100 of about 4,272,554 (282)

Experimental Study on the Mechanical Properties of Rock–Concrete Composite Specimens under Cyclic Loading

Buildings
The foundations of bridges and other tall buildings are often subjected to cyclic loads. Therefore, it is essential to investigate the mechanical properties of rock–concrete composite foundations under cyclic loads. In this paper, uniaxial cyclic loading
Hongjun Li, Baoyun Zhao, Zhengjun Hou, Hongyao Min   +3 more
doaj   +1 more source

Principal component analysis and perturbation theory–based robust damage detection of multifunctional aircraft structure [PDF]

, 2013
A fundamental problem in structural damage detection is to define an efficient feature to calculate a damage index. Furthermore, due to perturbations from various sources, we also need to define a rigorous threshold whose overtaking indicates the ...
HAJRYA, Rafik, MECHBAL, Nazih
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Modelling of Dynamic Behaviour of Orthotropic Metals Including Damage and Failure [PDF]

, 2012
A physically based material model for metals, with elastic plastic and damage/failure orthotropy is proposed in this paper. The model is defined within the frameworks of irreversible thermodynamics and configurational continuum mechanics and integrated ...
Djordjevic, Nenad, Vignjevic, Rade, Panov, Vili   +2 more
core   +1 more source

Evolution law for anisotropic damage

, 1999
Summary: We give a formulation for anisotropic damage in the framework of the principle of strain equivalence. The damage variable is still related to the surface density of microcracks and microvoids, and, as its evolution is governed by the plastic strain, it is represented by a second-order tensor and is orthotropic.
Lemaitre, Jean, Desmorat, Rodrigue, Sauzay, Maxime   +2 more
openaire   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Influence of pore-fracture structure characteristics of coal rock on its damage evolution law

Meitan kexue jishu
The development and expansion of fractures in coal rocks are the primary causes of mining disasters, such as gas outbursts, rock bursts, and instability of coal pillars.
Yiqing ZHAO, Wenjing QIN, Aibing JIN, Zhiguo CAO, Jinbo LIU, Kun QIN   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source