Results 71 to 80 of about 288,682 (268)

Study on Physical and Mechanical Properties and Deterioration Model of Deep Gray Sandstone under Freeze-Thaw Action

open access: yesDonghua Ligong Daxue Xuebao. Ziran Kexue Ban
[Objective] Rock engineering in cold area is not only affected by its own in-situ stress, but also by long-term freeze-thaw damage, which seriously affects engineering safety.
CHEN Wenzhao, TAN Yuanyuan
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Study on the Dynamic Mechanical Properties of Deep-Seated Rocks Under Coupled Confining Pressure and Loading Rate

open access: yesApplied Sciences
Deep rock engineering faces the combined challenges of high in situ stress and dynamic disturbances. However, traditional constitutive models treat confining pressure and rate effects independently, leading to significant prediction errors under high ...
Xuhui Li   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Plastic Damage Evolution of Flexible Casing Pile Utilized in Karst Area Under Vertical Loading

open access: yesApplied Sciences
Flexible casing piles can form locally enlarged sections by expanding flexible casings during concrete casting, thereby filling karst cavities and improving the adaptability and bearing capacity of pile foundations in karst areas.
Tao Wu   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Evolution law for anisotropic damage

open access: yes, 1999
Summary: We give a formulation for anisotropic damage in the framework of the principle of strain equivalence. The damage variable is still related to the surface density of microcracks and microvoids, and, as its evolution is governed by the plastic strain, it is represented by a second-order tensor and is orthotropic.
Lemaitre, Jean   +2 more
openaire   +2 more sources

Thermo-Mechanical Behavior of Sandstone and Its Implications for the Stability of Underground Gasification Cavities Under Unloading Conditions

open access: yesApplied Sciences
The extreme thermal environment during the underground coal gasification (UCG) process poses a severe threat to the stability of the gasification cavity and the integrity of the surrounding rock.
Jiakun Lv   +6 more
doaj   +1 more source

Constitutive modeling of cortical bone considering anisotropic inelasticity and damage evolution

open access: yesMechanical Engineering Journal, 2017
Researchers have conducted finite element (FE) analyses with human models to predict injuries due to traffic accidents or falling. In most of their analyses, cortical bone was simply modeled as a general isotropic elastoplastic material. In this study, a
Noritoshi ATSUMI   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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