Results 51 to 60 of about 4,272,554 (282)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Influence of dynamic disturbance on rock creep from time, space and energy aspects

Geomatics, Natural Hazards & Risk, 2022
In order to explore the influence of dynamic disturbance on creep behavior of rock, the creep damage evolution in rock under the dynamic disturbance are reproduced with creep damage model.
Zhen Yang, Wancheng Zhu, Kai Guan, Baoxu Yan, Hanwen Jia   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis of Damage Development Process Under Influence of Single Fracture of Loaded Similar Materials

Meikuang Anquan, 2020
In order to reveal the meso-damage mechanism of physical simulation of coal and rock dynamic disasters, using YYW- Ⅱ uniaxial compression tester and PCIE-8 acoustic emission (AE) monitoring system, the damage space development of samples with different ...
CHENG Xiaoyu
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modified Non-Local Damage Model: Resolving Spurious Damage Evolution

Engineering Fracture Mechanics
Accurate prediction of damage and fracture evolution is critical for the safety design and preventive maintenance of engineering structures, however existing computational methods face significant limitations. On one hand, discrete damage and phase-field models are often computationally prohibitive for real world applications and they are less ...
Roshan Philip Saji, Panos Pantidis, Mostafa E. Mobasher   +2 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Damage evolution in marble under uniaxial compression monitored by Pressure Stimulated Currents and Acoustic Emissions

Fracture and Structural Integrity, 2019
The spatiotemporal evolution of damage in marble speci¬mens under uniaxial compression is monitored using Pressure Stimulated Currents (PSCs) and Acoustic Emissions (AEs). The novelty of the study is the use of an integrated grid of sensors (instead of a
Ilias Stavrakas, Stavros K. Kourkoulis, Dimos Triantis   +2 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source