Results 61 to 70 of about 289,419 (268)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Study on the Dynamic Mechanical Properties of Deep-Seated Rocks Under Coupled Confining Pressure and Loading Rate

Applied Sciences
Deep rock engineering faces the combined challenges of high in situ stress and dynamic disturbances. However, traditional constitutive models treat confining pressure and rate effects independently, leading to significant prediction errors under high ...
Xuhui Li, Yunhou Sun, Jun Shen, Zailin Yang, Yong Mei, Chenliang Li, Shengyi Cong   +6 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Thermo-Mechanical Behavior of Sandstone and Its Implications for the Stability of Underground Gasification Cavities Under Unloading Conditions

Applied Sciences
The extreme thermal environment during the underground coal gasification (UCG) process poses a severe threat to the stability of the gasification cavity and the integrity of the surrounding rock.
Jiakun Lv, Bing Chen, Yedan Lu, Jian Ma, Chengye Yang, Jingong Ma, Zhaofei Xu   +6 more
doaj   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Plastic Damage Evolution of Flexible Casing Pile Utilized in Karst Area Under Vertical Loading

Applied Sciences
Flexible casing piles can form locally enlarged sections by expanding flexible casings during concrete casting, thereby filling karst cavities and improving the adaptability and bearing capacity of pile foundations in karst areas.
Tao Wu, Yueran Hao, Ying Wang, Lulu Zhang, Fengyu Zhang, Yunpeng Zhang   +5 more
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Structural Response of Stiffened Panels Under Repeated Impacts from Rigid and Ice Hammers: An Experimental and Numerical Study

Journal of Marine Science and Engineering
Repeated-impact tests were carried out on a typical stiffened panel using both a wedge-shaped ice indenter and, for comparison, a rigid steel indenter under identical conditions. The tests were performed on a drop-weight impact system under a mass-loaded
Nan Zhao, Yuwen Xu, Fei Li, Tongqiang Yu, Kun Liu   +4 more
doaj   +1 more source

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel, Mieke Rijken, Marietta Kokla, Charlotte Sleurs, Jurgen Lemiere, Line Elmerdahl Frederiksen, Luzius Mader, Cecilia Follin, Sara Oberti, Jeanette Falck Winther, Selina R. van den Oever, Leontien C. M. Kremer, Helena J. H. van der Pal, Peter Spreeuwenberg, Eline Bouwman, Jeroen te Dorsthorst, Samira Essiaf, Elizabeth A. M. (Lieke) Feijen, Hannah Gsell, Riccardo Haupt, Maria van Helvoirt, Rosella P. M. G. Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Monica Muraca, Marleen Renard, Carina Schneider, Roderick Skinner, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jacqueline Loonen, Saskia M. F. Pluijm, Katharina Roser, the PanCareFollowUp consortium   +36 more
wiley   +1 more source

Characterization of acoustic emission signals in recycled axial compression-damaged polypropylene fiber-reinforced concrete

Meitan xuebao
To investigate the damage evolution characteristics of polypropylene fiber reinforced concrete (PFRC) under dynamic compressive loading, a series of reciprocating axial compression tests on prismatic specimens were conducted.
Lina WEN, Dong XIAO, Jin ZHAO, Hongyuan LIU, Yan FENG   +4 more
doaj   +1 more source