Results 51 to 60 of about 4,651,346 (275)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Crack detection in beam-like structures by nonlinear harmonic identification
Fracture and Structural Integrity, 2014 The dynamic behavior of beam-like structures with fatigue cracks forced by harmonic excitation is characterized by the appearance of sub and super-harmonics in the response even in presence of cracks with small depth.
Paolo Casini +2 more
doaj
Applied Sciences, 2022 A new damage identification method is proposed to solve the problem of no correspondence between the element division form of the finite element model and the actual damage location.
Hongyin Yang +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A data fusion based approach for damage detection in linear systems
Fracture and Structural Integrity, 2014 The aim of the present paper is to propose innovative approaches able to improve the capability of classical damage indicators in detecting the damage position in linear systems.
Ernesto Grande, Maura Imbimbo
doaj
Seismic Damage Identification Method for Curved Beam Bridges Based on Wavelet Packet Norm Entropy
Sensors, 2021 Curved beam bridges, whose line type is flexible and beautiful, are an indispensable bridge type in modern traffic engineering. Nevertheless, compared with linear bridges, curved beam bridges have more complex internal forces and deformation due to the ...
Tongfa Deng +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Applied SciencesIn the field of bolt loosening detection, although some progress has been made, there are still challenges such as high operational complexity, single feature extraction methods, and insufficient analysis model performance, especially in large steel ...
Zepu Jiang, Zhiwei Zhu, Debing Zhuo
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source