Results 61 to 70 of about 740,837 (265)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Applied Sciences, 2022 A new damage identification method is proposed to solve the problem of no correspondence between the element division form of the finite element model and the actual damage location.
Hongyin Yang +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Crack detection in beam-like structures by nonlinear harmonic identification
Fracture and Structural Integrity, 2014 The dynamic behavior of beam-like structures with fatigue cracks forced by harmonic excitation is characterized by the appearance of sub and super-harmonics in the response even in presence of cracks with small depth.
Paolo Casini +2 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A data fusion based approach for damage detection in linear systems
Fracture and Structural Integrity, 2014 The aim of the present paper is to propose innovative approaches able to improve the capability of classical damage indicators in detecting the damage position in linear systems.
Ernesto Grande, Maura Imbimbo
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Detection of structural damage using the exponential sine sweep method [PDF]
, 2013 Structural damages can result in nonlinear dynamical responses. Thus, estimating the nonlinearities generated by damages potentially allows detecting them.
HAJRYA, Rafik +2 more
core
Effect of Ductile Damage Evolution in Sheet Metal Forming: Experimental and Numerical Investigations [PDF]
, 2010 The numerical simulation based on the Finite Element Method (FEM) is widely used in academic institutes and in the industry. It is a useful tool to predict many phenomena present in the classical manufacturing forming processes such as necking, fracture,
Sébastien Mistou +9 more
core +1 more source
Damage identification tools for cable-stayed bridges: monitoring the key structural elements
, 2022 Shenton, Harry W., IIIChajes, Michael J.In this, the era of the 4th Industrial Revolution (Industry 4.0), Structural Health Monitoring (SHM) has enabled the evolution of the maintenance of our infrastructure, and in particular of bridges.
Aloupis, Christos
core +1 more source