Results 141 to 150 of about 1,735,830 (308)

Study on Damage Index for Beam–Column Joints with Flush End-Plate Connections

Buildings
Experimental results from 109 flush end-plate (FEP) connections were analyzed to investigate the failure modes and damage index of FEP connections across various damage states.
Jizhi Su, Jinpu Zhou, Weiran Liu, Yong Li, Haifeng Yu, Qilian Li   +5 more
doaj   +1 more source

Lichen Planus Activity and Damage Index (LiPADI)-Creation of the Questionnaire. [PDF]

J Clin Med, 2021
Stępień K, Żabska E, Rahnama-Hezavah M, Reich A.   +3 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Association between SLICC/ACR damage index and outcomes for lupus patients after cardiac valve surgery. [PDF]

Interact Cardiovasc Thorac Surg, 2022
Hu SY, Cheng CF, Yang KJ, Wang CH, Chi NH, Hsu RB, Chen YS, Yu HY.   +7 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A domain damage index to prioritizing the pathogenicity of missense variants. [PDF]

Hum Mutat, 2021
Chen HC, Wang J, Wang J, Liu Q, Shyr Y.
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Circulating irisin levels in functional hypothalamic amenorrhea: a new bone damage index? A pilot study. [PDF]

Endocrine, 2022
Notaristefano G, Merola A, Scarinci E, Ubaldi N, Ranalli M, Tropea A, Diterlizzi A, Fabozzi SM, Alesiani O, Silvestrini A, Mordente A, Capristo E, Lanzone A, Apa R.   +13 more
europepmc   +1 more source

Dynamic characterisation of a damaged composite structure with stiffeners employing fibre bragg gratings [PDF]

, 2011
One of the key issues in composite structures for aircraft applications is the early detection and localisation of damage. Often service induced damage does not involve visible plastic deformation, but internal matrix related damage, like transverse ...
Akkerman, R., Boer, A. de, Grooteman, F.P., Loendersloot, R., Ooijevaar, T.H., Warnet, L.L.   +5 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source