Results 161 to 170 of about 1,264,657 (267)

Evolution of Pore Structure and Damage Mechanism Analysis of Cement-Silt-Modified Eolian Sand Under Freeze-Thaw Cycles. [PDF]

Materials (Basel)
Li X, Miao C, Shi Z.
europepmc   +1 more source

Freeze-Thaw Damage Mechanism Analysis of SBS Asphalt Mixture Containing Basalt Fiber and Lignocellulosic Fiber Based on Microscopic Void Characteristics. [PDF]

Polymers (Basel), 2023
Wang W, Yang L, Cui H, Wu F, Cheng Y, Liang C.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Hot Corrosion Behavior and Damage Mechanism on Yield Property of Nickel-Based Superalloy. [PDF]

Materials (Basel)
Meng X, Lyu S, Xie X, Tang C, Yu W, Hou W, Wang C, Qu J, Du J.   +8 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Fracture Behavior and Damage Mechanism of Red Sandstone under Loading: An Experimental and DEM Study. [PDF]

ACS Omega
Wu D, Jiang XY, Hu HS, He TH, Yang Y, Yang GL.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Dynamic response and damage mechanism of reinforced concrete beam bridges under rockfall impacts. [PDF]

Sci Rep
Wang H, Lu W, Zhan W.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A Study of Sperm DNA Damage Mechanism Based on miRNA Sequencing. [PDF]

Am J Mens Health
Liu F, Ma M, Li L, Zhang Y, Shang Y, Yuan Q, Ju B, Wang Z.   +7 more
europepmc   +1 more source