Results 81 to 90 of about 1,264,657 (267)

Freeze–Thaw Damage Model and Mechanism of Rubber Concrete with Recycled Brick–Concrete Aggregate

Buildings
This study investigated the effects of rubber substitution ratios (0%, 5%, 10%, 15%) on the frost resistance of rubber concrete with recycled brick–concrete aggregate (BRC).
Jiayu Zeng, Jiangfeng Dong, Siwei Du, Shucheng Yuan, Kunpeng Li, Xinyue Zhang, Xinyu Chen   +6 more
doaj   +1 more source

Experimental and Simulation Study of Low-Velocity Impact on Glass Fiber Composite Laminates with Reinforcing Shape Memory Alloys at Different Layer Positions

Applied Sciences, 2018
The effects of shape memory alloy (SMA) wires on the damage behavior of glass fibers/epoxy resin composite laminates for the case of low-velocity impact are investigated experimentally and numerically.
Min Sun, Mengzhou Chang, Zhenqing Wang, Hao Li, Xiaokun Sun   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

DNA damage and repair mechanism. [DNA damage and repair mechanisms] [PDF]

, 1976
The ability of cells to survive in an environment specifically damaging to its DNA can be attributed to a variety of inherent repair mechanisms. This is a form of repair in which alterations are directly reversed to their original form. This reversibility is exemplified by the photoreactivation of ultraviolet-induced pyrimidine dimers.
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Pore fracture structure evolution and damage failure mechanism of hot dry rock induced by temperature impact effect

Meitan xuebao
The geothermal resource originating from the hot dry rock is a form of clean and renewable energy, which has the advantages of stable, efficient, and permanent.
Yong SUN, Cheng ZHAI, Yuzhou CONG, Yangfeng ZHENG, Wei TANG, Shuai WANG, Yongshuai LAI, Yu WANG, Aikun CHEN   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Acoustic Emission and Digital Image Correlation-Based Study for Early Damage Identification in Sandwich Structures

Applied Sciences
Understanding the deterioration and predominant damage mechanisms of structures is highly relevant, especially for safety-critical components. Non-Destructive Testing (NDT) plays a crucial role in assessing and monitoring their integrity by evaluating ...
Aitor García de la Yedra, Igor Erro, Javier Vivas, Oier Zubiri, Xabier Zurutuza, Ryan Sommerhuber, Matthias Kettner   +6 more
doaj   +1 more source