Results 181 to 190 of about 1,333,549 (315)

Water-induced damage mechanism and dual-radius grouting control of weakly cemented argillaceous roadways in Western China. [PDF]

Sci Rep
Yu Z, Lun Z, Zhang Z, Zhang W, Wang S, Zhao L, Liu S.   +6 more
europepmc   +1 more source

Identification of NOL-Ring Composite Materials' Damage Mechanism Based on the STOA-VMD Algorithm. [PDF]

Polymers (Basel), 2023
Jiang P, Li H, Yan X, Zhang L, Li W.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Strength hardening and damage mechanism of semiwetted coal under cyclic loads with different initial stress levels. [PDF]

Sci Rep
Lv F, Zhang Y, Kong F, Li X, Zou Q.
europepmc   +1 more source

Damage Mechanism of HgCdTe Focal Plane Array Detector Irradiated Using Mid-Infrared Pulse Laser. [PDF]

Sensors (Basel), 2023
Zhang Y, Zheng C, Liu Y, Wang Y, Xu Y, Shao J.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Damage Mechanism and Modeling of CFRP Laminates Impacted by Single Waterjets: Effect of the Impact Direction. [PDF]

Materials (Basel)
Hou N, Li Y, Liu P.
europepmc   +1 more source

In vitro investigation of stone ablation efficiency, char formation, spark generation, and damage mechanism produced by thulium fiber laser. [PDF]

Urolithiasis, 2023
Chen J, Mishra A, Medairos R, Antonelli J, Preminger GM, Lipkin ME, Zhong P.   +6 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Study on Damage Mechanism of Fiber Concrete with Initial Pores. [PDF]

Materials (Basel)
Hu A, Du X, Wang F, Li J, Zhang T, Li Y.
europepmc   +1 more source