Results 211 to 220 of about 1,333,549 (315)

Damage mechanism and evolution model of geopolymer stabilized coarse grained fillings subjected to repeated freeze-thaw actions. [PDF]

Sci Rep
Wang S, Xiang Y, Wu Z, Hui H, Hou S, Sun Z.   +5 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Strength of Fibrous Composites with an Impact Damage

Some aspects of a problem mechanical, mainly, impact damage of a composite material and their influence to the remaining abilities of a structure are considered in present article.
Pavelko, Igors, Pavelko, Vitālijs, Chatys, Rafal   +2 more
core  

Microstructure Evolution and Damage Mechanism of DD9 Single Crystal Superalloy-Thermal Barrier Coating System Under High Temperature Oxidation: A Comparative Study with DD6. [PDF]

Materials (Basel)
Li P, Xin Z, Sun F, Jin X, Zhang C.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The First Chalcone Derivatives of Valine-Based Spiro-Cyclotriphosphazenes: In Vitro Cytotoxic Properties, Molecular Docking and DNA Damage Mechanism Studies. [PDF]

J Biochem Mol Toxicol
Yücel Y, Şeker FS, Erden BA, Özdemir M, Tekin Ç, Çalışkan E, Tekin S, Koran K, Biryan F.   +8 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The Overload Effect on the Crack Tip Damage Mechanism in a 7075 Aluminum Alloy. [PDF]

Materials (Basel)
Xie C, Zheng Z, Li L, Sun T.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Microstructural Evolution and Damage Mechanism of Water-Immersed Coal Based on Physicochemical Effects of Inorganic Minerals. [PDF]

Materials (Basel)
Chen X, Liu Z, Li T, Ma J, Hu J.
europepmc   +1 more source