Results 231 to 240 of about 3,477,793 (285)

DNA repair: models for damage and mismatch recognition

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2000
Maintaining the integrity of the genome is critical for the survival of any organism. To achieve this, many families of enzymatic repair systems which recognize and repair DNA damage have evolved. Perhaps most intriguing about the workings of these repair systems is the actual damage recognition process.
Jaqueline Barton, Scott R Rajski
exaly   +4 more sources

Artificial immune pattern recognition for structure damage classification [PDF]

Computers and Structures, 2009
Damage detection in structures is one of the research topics that have received growing interest in research communities. While a number of damage detection and localization methods have been proposed, very few attempts have been made to explore the ...
Chuanzhi Zang
exaly   +2 more sources

A hybrid immune model for unsupervised structural damage pattern recognition

Expert Systems With Applications, 2011
This paper presents an unsupervised structural damage pattern recognition approach based on the fuzzy clustering and the artificial immune pattern recognition (AIPR). The fuzzy clustering technique is used to initialize the pattern representative (memory
Chuanzhi Zang
exaly   +2 more sources

Frequency response function based damage identification using principal component analysis and pattern recognition technique

Engineering Structures, 2014
Pattern recognition is a promising approach for the identification of structural damage using measured dynamic data. Much of the research on pattern recognition has employed artificial neural networks (ANNs) and genetic algorithms as systematic ways of ...
David Thambiratnam, Tommy H T Chan
exaly   +2 more sources

Damage recognition by UV damage endonuclease from Schizosaccharomyces pombe

DNA Repair, 2009
UV damage endonuclease (UVDE) from Schizosaccharomyces pombe initiates repair of UV lesions and abasic sites by nicking the DNA 5' to the damaged site. In this paper we show that in addition UVDE incises DNA containing a single-strand nick or gap, but that the enzymatic activity on these substrates as well as on abasic sites strongly depends on the ...
Keti, Paspaleva, Geri F, Moolenaar, Nora, Goosen   +2 more
openaire   +2 more sources

Specificity of damage recognition and catalysis of DNA repair

Computers & Chemistry, 2000
A common feature of DNA repair enzymes is their ability to recognize the damage independently of sequence in which they are found. The presence of a flipped out base inserted into the protein in several DNA-enzyme complexes suggests a contribution to enzyme specificity.
Osman R., Fuxreiter M., Luo N.
openaire   +2 more sources

The recognition of DNA damage

Current Opinion in Genetics & Development, 1996
DNA strand breaks are potentially mutagenic and must, therefore, be recognized and repaired. Recent work has identified DNA polymerase epsilon, Ku, and proteins such as DNA-PKcs, Mec1 and Tel1 as key players in DNA damage recognition pathways. Studies on these and other factors have provided important insights into the mechanisms of DNA repair and how ...
openaire   +2 more sources

Recognition of overlapping patterns and focal hemisphere damage

Neuropsychologia, 1976
Abstract 204 Ss entered this research, subdivided in controls ( N = 44) and hemisphere damaged patients ( N = 160). A meaningful and a meaningless patterns version of the Poppelreuter-Ghent Test were employed and the answers were worked out in the frame of the Signal Detectability Theory.
E, Bisiach, E, Capitani, P, Nichelli, H, Spinnler   +3 more
openaire   +2 more sources