Results 1 to 10 of about 5,117,673 (294)

Cognitive impairment, dizziness, and unsteadiness in hypertensive patients

Неврология, нейропсихиатрия, психосоматика, 2020
Hypertension is a widespread disease related to modifiable vascular risk factors for stroke and chronic cerebrovascular diseases. The pathogenetic basis of brain damage in hypertension is cerebral microangiopathy that leads to vascular cognitive ...
L. M. Antonenko, N. V. Vakhnina, D. O. Gromova   +2 more
doaj   +1 more source

Indoxyl Sulfate-Mediated Blood–Brain Barrier Damage in Chronic Kidney Disease

Toxins
Chronic kidney disease is associated with neurovascular complications including cognitive impairment, potentially involving blood–brain barrier (BBB) impairment.
Leah Hernandez, Camillo Tancredi Strizzi, Miriam Rosina, Angelina Schwarz, Nina Kronqvist, Samsul Arefin, Peter Stenvinkel, Karolina Kublickiene   +7 more
doaj   +1 more source

Sirtuins and neuronal DNA damage under experimental chronic cerebral hypoperfusion

Patologìâ, 2019
Chronic brain hypoperfusion (ChCH) is a risk factor for central nervous system (CNS) diseases, such as chronic brain ischemia, degenerative diseases, and others, in this connection, the study of its pathophysiological mechanisms is an actual problem ...
O. Yu. Harmatina, Т. Yu. Voznesenska, N. H. Hrushka, О. А. Kondratska, А. H. Portnychenko   +4 more
doaj   +1 more source

Stroke and brain atrophy in chronic Chagas disease patients: A new theory proposition

Dementia & Neuropsychologia
Chagas disease (CD) remains a major cause of cardiomyopathy and stroke in developing countries. Brain damage in CD has been attributed exclusively to the effects of structural heart disease on the brain, including cardioembolism and low cardiac output ...
Jamary Oliveira-Filho
doaj   +1 more source

Gastrostomias e fundoplicaturas: estudo retrospectivo de 5 anos em pacientes pediátricos no Hospital Municipal Jesus/RJ

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Analisar o quadro clínico, morbi-mortalidade e resultados da fundoplicatura gastroesofágica em crianças, com ênfase em portadores de encefalopatias crônicas.
Lisieux Eyer de Jesus, Paulo César Costa Monteiro, Renata Restay Siqueira, Elisiane Bezerra Marinho, Pedro Augusto Vital Nogueira   +4 more
doaj   +1 more source

Necroptosis and microglia activation after chronic ischemic brain injury in mice

European Journal of Inflammation, 2017
Microglia, which are the resident macrophages and the first line of defense in the brain, can be activated within hours and migrate toward the injury sites after acute and chronic ischemic brain injury.
Shehong Zhang, Yuyang Wang, Hongyu Xie, Qing Yu, Junfa Wu, Yi Wu, Yulian Zhu   +6 more
doaj   +1 more source

Inflammatory projections after focal brain injury trigger neuronal network disruption: An 18F-DPA714 PET study in mice

NeuroImage: Clinical, 2018
Due to the heterogeneous pathology of traumatic brain injury (TBI), the exact mechanism of how initial brain damage leads to chronic inflammation and its effects on the whole brain remain unclear.
Sanae Hosomi, Tadashi Watabe, Yuki Mori, Yoshihisa Koyama, Soichiro Adachi, Namiko Hoshi, Mitsuo Ohnishi, Hiroshi Ogura, Yoshichika Yoshioka, Jun Hatazawa, Toshihide Yamashita, Takeshi Shimazu   +11 more
doaj   +1 more source

Microglia Involvement into Acute and Chronic Brain Damage in Diabetic Rats: Impact of GLP-1RA and SGLT-2i

Frontiers in Bioscience-Landmark
Background: Acute and chronic brain damage in type 2 diabetes mellitus (DM) determines the need to investigate the neuroprotective potential of glucose-lowering drugs.
Anna Simanenkova, Oksana Fuks, Natalya Timkina, Alina Islamova, Dina Sufieva, Оlga Kirik, Dmitrii Korzhevskii, Timur Vlasov, Tatiana Karonova   +8 more
doaj   +1 more source

Roles of White Matter in Central Nervous System Pathophysiologies

ASN Neuro, 2012
The phylogenetic enlargement of cerebral cortex culminating in the human brain imposed greater communication needs that have been met by the massive expansion of WM (white matter).
Carlos Matute, Bruce R Ransom
doaj   +1 more source

A self-insertable 5-μm-diameter flexible microneedle for minimally invasive and stable in vivo neural recording

Sensing and Bio-Sensing Research
Implantable intracortical microelectrodes are essential tools for neuroscience research, clinical applications, and brain–computer interfaces. Achieving stable chronic recording of neuronal activity, however, remains challenging due to tissue damage ...
Hinata Sasaki, Sayaki Shimizu, Rexy Alvian Nerchan, Koji Yamashita, Naohiro Takahashi, Rina Chinone, Yurika Kurashige, Rika Numano, Kowa Koida, Masahiro Ohsawa, Takeshi Kawano   +10 more
doaj   +1 more source