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Recognition of DNA Damage During Replication

1997
DNA lesions can be eliminated from metazoan organisms by DNA repair processes or by cell death. If DNA damage remains unrepaired and cells survive, the efficiency and fidelity of essential nuclear functions is seriously threatened. In particular, replication of damaged DNA represents a major mechanism of genetic instability.1,2 Covalent modification of
openaire   +1 more source

Intragenomic Hierarchies of DNA Damage Recognition

1997
Nuclear DNA in mammalian cells is a highly nonuniform substrate with respect to its susceptibility to genotoxic reactions. For example, cyclobutane pyrimidine dimer formation is modulated at the nucleosomal level with a 10.3 base average periodicity.1,2 The frequency of pyrimidine(6-4)pyrimidone photoproducts is greater in nuclease-sensitive DNA than ...
openaire   +1 more source

Dynamics of DNA Damage Recognition

2005
Roman Osman   +2 more
openaire   +1 more source

Damaged Letter Recognition Methodology - A Comparison Study

Proceedings of the 5th International Joint Conference on Computational Intelligence, 2013
Eva Volná   +4 more
openaire   +2 more sources

‘Close-fitting sleeves’: DNA damage recognition by the UvrABC nuclease system

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005
Caroline Kisker   +2 more
exaly  

Recognition of early oral cancer

Ca-A Cancer Journal for Clinicians, 1965
Donald P Shedd, Morton M Kligerman
exaly  

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