Results 91 to 100 of about 875,259 (309)

Comparison of toughened composite laminates using NASA standard damage tolerance tests [PDF]

open access: yes, 1984
The proposed application of composite materials to transport wing and fuselage structures prompted the search for tougher materials having improved resistance to impact damage and delamination.
Chapman, A. J., III   +2 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Modelling of impact damage and permanent indentation on laminate composite plate [PDF]

open access: yes, 2010
This paper deals with impact damage and permanent indentation modelling. A model enabling the formation of damages developing during a low velocity / low energy impact test on laminate composite panels has been elaborated.
Barrau, Jean-Jacques   +2 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Design of anisotropic plates for improved damage tolerance [PDF]

open access: yes
An analytical study is presented showing the effects of the notch tip geometry on the location and direction of crack growth from an existing notch in a unidirectional fibrous composite modeled as a homogeneous, anisotropic, elastic material. Anisotropic
Guerdal, Zafer
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Tolerance to mechanical damage in ten herbaceous grassland plant species

open access: yesPlant, Soil and Environment, 2012
The establishment of plants with high damage tolerance may provide a means for soil protection on sites exposed to strong disturbance. In a pot experiment, we investigated the tolerance to mechanical strain of ten grassland plant species representing ...
L. Breitsameter   +3 more
doaj   +1 more source

Development of integrated database management and expert system for selection of materials to meet durability and damage tolerance requirements(completion Report) [PDF]

open access: yes, 1993
This is the completion report of the project taken under the Grants-in-Aid scheme of the Aeronautics Research and Development Board. This report enunciates in detail the methodology adopted for arriving at the durability and damage tolerance values of ...
Raju, KN
core  

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